COMPOUNDS AND RELATED METHODS FOR MUTANT p53 REACTIVATION

Title:

COMPOUNDS AND RELATED METHODS FOR MUTANT p53 REACTIVATION

Document Type and Number:

WIPO Patent Application WO2005042481

Kind Code:

A3

Abstract:

Ketoamine compounds and related methods for reactivation of tumor suppressor protein p53.

Inventors:

APPELLA DANIEL H (US)
MYERS MICHAEL C (US)
ZAMBETTI GERALD P (US)

Application Number:

PCT/US2004/036262

Publication Date:

August 25, 2005

Filing Date:

November 01, 2004

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV NORTHWESTERN (US)
APPELLA DANIEL H (US)
MYERS MICHAEL C (US)
ZAMBETTI GERALD P (US)

International Classes:

A61K31/138; A61K31/16; A61K31/24; C07C221/00; C07C225/06; C07C229/22; C07C233/00; C07C233/31; C07C271/18; C07C271/22; C07D; (IPC1-7): C07C221/00; C07C233/00; A61K31/24

Foreign References:

US2562107A

1951-07-24

Download PDF:

View/Download PDF PDF Help

Previous Patent: N-SUBSTITUTED PYRAZOLYL CARBOXANILIDES

Next Patent: [R-(R*,R*)]-2-(4-FLUOROPHENYL)-BETA, DELTA-DIHYDROXY-5-((1-METHYLETHYL) -3-PHENYL-4-[(PHENYLAMINO) C...