Title:
CALIBRATION OF MASS SPECTROMETRY SYSTEMS
Document Type and Number:
WIPO Patent Application WO/2021/140178
Kind Code:
A9
Abstract:
Systems for analyzing a biological sample include a separation unit configured to separate a component from the biological sample, an ionization unit configured to generate a plurality of ions from the component, an adjustable mass-selective filtering element, a detector configured to detect ions that pass through the mass-selective filtering element, and a controller connected to the mass- selective filtering element and to the detector, where the controller is configured so that during operation of the system, the controller adjusts the mass-selective filtering element and activates the detector to measure at least three different ion signals corresponding to the plurality of ions, and determines a mass axis shift of the system based on the at least three different ion signals.
Inventors:
ARENS NADJA (DE)
INTELMANN DANIEL (DE)
INTELMANN DANIEL (DE)
Application Number:
PCT/EP2021/050237
Publication Date:
October 28, 2021
Filing Date:
January 08, 2021
Export Citation:
Assignee:
HOFFMANN LA ROCHE (CH)
ROCHE DIAGNOSTICS GMBH (DE)
ROCHE DIAGNOSTICS OPERATIONS INC (US)
ROCHE DIAGNOSTICS GMBH (DE)
ROCHE DIAGNOSTICS OPERATIONS INC (US)
International Classes:
H01J49/00; H01J49/42
Attorney, Agent or Firm:
STÖßEL, Matthias (DE)
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