CANCER-CELL PROLIFERATION INHIBITOR AND CANCER-CELL-PROLIFERATION INHIBITION ENHANCER

Title:

CANCER-CELL PROLIFERATION INHIBITOR AND CANCER-CELL-PROLIFERATION INHIBITION ENHANCER

Document Type and Number:

WIPO Patent Application WO/2023/153020

Kind Code:

A1

Abstract:

One of the problems addressed by the present invention is to provide a cancer-cell proliferation inhibitor that contains a compound that is derived from a food component and that is highly safe. The description of the present application discloses a cancer-cell proliferation inhibitor that contains an immune checkpoint inhibitor and at least one of 5-(3,5-dihydroxyphenyl)-γ-valerolactone represented by formula (I), a salt of said compound, and a conjugate of said compound.

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Inventors:

TACHIBANA HIROFUMI (JP)
TAKAGAKI AKIKO (JP)

Application Number:

PCT/JP2022/037606

Publication Date:

August 17, 2023

Filing Date:

October 07, 2022

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Assignee:

UNIV KYUSHU NAT UNIV CORP (JP)
MITSUI NORIN KK (JP)

International Classes:

A61K45/00; A61K31/365; A61K39/395; A61P35/00; A61P43/00; A23L33/10

Foreign References:

JP2016160238A

2016-09-05

Other References:

MELAIU OMBRETTA, LUCARINI VALERIA, CIFALDI LOREDANA, FRUCI DORIANA: "Influence of the Tumor Microenvironment on NK Cell Function in Solid Tumors", FRONTIERS IN IMMUNOLOGY, vol. 10, 21 January 2020 (2020-01-21), pages 3038, XP093084167, DOI: 10.3389/fimmu.2019.03038

Attorney, Agent or Firm:

KAMIMURA Yoichiro (JP)

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