CANCER CELL PROLIFERATION INHIBITORS

WIPO Patent Application WO/1998/002419

A1

Compounds represented by general formula (1) or salts thereof which are useful as cancer cell proliferation inhibitors and remedies for cancer, because of having selective antagonisms against gastrin receptors and CCK-B receptors and showing an inhibitory effect on the proliferation of cancer cells, wherein, for example, R�1? represents halogeno, lower alkyl, lower alkoxy, hydroxy, nitro, trifluoromethyl, lower alkylthio, acyl, carboxy, mercapto or amino; R�2? represents hydrogen, lower alkyl, lower alkenyl, lower alkynyl, aryl or heterocycle; R�3? represents lower alkyl, cycloalkyl, aryl or heterocycle; R�4? represents hydrogen, lower alkyl, aryl or heterocycle; X and Y are the same or different and each represents -CH�2?-, -NH- or -O-; and n is an integer of from 0 to 4.

WO/2001/096298	1,2,4-TRISUBSTITUTED BENZENES AS INHIBITORS OF 15-LIPOXYGENASE
WO/2016/181348	COMBINATIONS COMPRISING A PYRROLIDINE-2,5-DIONE IDO1 INHIBITOR AND AN ANTI-BODY
WO/2005/030755	HETEROARYL-SUBSTITUTED 1,3-DIHYDROINDOL-2-ONE DERIVATIVES AND MEDICAMENTS CONTAINING THEM

CHIBA TSUTOMU (JP)

PCT/JP1997/002406

January 22, 1998

July 11, 1997

Click for automatic bibliography generation  

CHUGAI PHARMACEUTICAL CO LTD (JP)
CHIBA TSUTOMU (JP)

A61K31/404; C07D209/34; (IPC1-7): C07D209/34; A61K31/40; A61K31/405; A61K31/44; A61K31/445; A61K31/495; C07D209/40; C07D401/06; C07D401/12; C07D405/06

WO1995003285A1	1995-02-02
WO1995004720A2	1995-02-16
WO1995005359A1	1995-02-23

JPH0748349A	1995-02-21
JPH06339380A	1994-12-13
JPH0840908A	1996-02-13
JPH06321917A	1994-11-22
JPH07258081A	1995-10-09

Yuasa, Kyozo (Section 206 New Ohtemachi Building, 2-1, Ohtemachi 2-chom, Chiyoda-ku Tokyo 100, JP)

View/Download PDF      PDF Help

Previous Patent: PROCESS FOR THE SEPARATION OF A KETOXIME OR ALDOXIME FROM AN AMIDE

Next Patent: DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS