Title:
CANCER DIAGNOSIS KIT AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER
Document Type and Number:
WIPO Patent Application WO/2012/011778
Kind Code:
A2
Abstract:
The present invention relates to a composition for cancer diagnosis having a formulation for measuring the expression level of Chromosome 10 open reading frame 81 (C10orf81) gene mRNA or protein thereof, a kit for cancer diagnosis having the composition, a method for providing information on cancer diagnosis including a step for measuring the expression level of C10orf81 gene mRNA or the expression level of protein coded by the gene, and a method for screening pharmaceutical compositions for the prevention or the treatment of cancer including an expression inhibitor for the C10orf81 gene or an activity inhibitor for the protein thereof, and therapeutic agents for cancer. The present invention enables an accurate diagnosis of cancer by providing genes specific to stomach cancer, liver cancer, colorectal cancer, lung cancer, or prostate cancer, and diagnostic markers for determining the metastasis and prognosis of the cancer, and can be useful in the diagnosis and prognosis management of cancer. Also, the present invention enables the development of new bio-medicines having fewer side effects and customized anticancer drugs by providing a cancer-specific therapeutic agent capable of inhibiting the gene.
Inventors:
CHUNG, Kyung Sook (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
정경숙 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
WON, Mi Sun (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
원미선 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
AHN, Ji Won (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
안지원 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
KIM, Young Joo (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
정경숙 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
WON, Mi Sun (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
원미선 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
AHN, Ji Won (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
안지원 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
KIM, Young Joo (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
Application Number:
KR2011/005433
Publication Date:
January 26, 2012
Filing Date:
July 22, 2011
Export Citation:
Assignee:
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
한국생명공학연구원 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
CHUNG, Kyung Sook (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
정경숙 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
WON, Mi Sun (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
원미선 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
AHN, Ji Won (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
안지원 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
한국생명공학연구원 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
CHUNG, Kyung Sook (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
정경숙 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
WON, Mi Sun (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
원미선 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
AHN, Ji Won (52 Eoeun-dong, Yuseong-gu, Daejeon 305-806, 305-806, KR)
안지원 (대전광역시 유성구 어은동 52번지, 305-806 Daejeon, 305-806, KR)
International Classes:
C12Q1/68; A61K48/00; C12N15/12; G01N33/574
Attorney, Agent or Firm:
SON, Min (HANOL Intellectual Property & Law, 6th Floor City Air Tower,159-9 Samseong-dong, Gangnam-gu, Seoul 135-973, 135-973, KR)
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