Title:
CANCER DIAGNOSIS METHOD AND SYSTEMS USING SECOND HARMONIC GENERATION MEASUREMENTS
Document Type and Number:
WIPO Patent Application WO/2023/141623
Kind Code:
A3
Abstract:
Methods, devices and systems are described that enable identification of cancerous or pre-cancerous colon tissue. The described methods and systems rely on non-imaging, randomly sampled second harmonic generation (SHG) intensity measurements that are sufficient for differentiating between tumor and normal tissue. The disclosed methods and system further provide for angle-resolved SHG measurements associated with forward and backward scattered light that eliminate the need to obtain paired normal and cancer-suspicious measurements in each patient using the described techniques.
Inventors:
MONTAGUE JENNA (US)
BARTON JENNIFER (US)
SHIR HASINA (US)
BARTON JENNIFER (US)
SHIR HASINA (US)
Application Number:
PCT/US2023/061088
Publication Date:
October 19, 2023
Filing Date:
January 23, 2023
Export Citation:
Assignee:
UNIV ARIZONA (US)
International Classes:
A61B1/31; A61B1/04; A61B1/06; G02B27/09; G06T7/11; G06T7/136
Foreign References:
| US20130057873A1 | 2013-03-07 | |||
| US20130006056A1 | 2013-01-03 | |||
| US20170138860A1 | 2017-05-18 | |||
| US20100312057A1 | 2010-12-09 | |||
| US20070263406A1 | 2007-11-15 |
Other References:
CAMPAGNOLA: "Second Harmonic Generation Imaging Microscopy: Applications to Diseases Diagnostics", ANAL. CHEM., vol. 83, no. 9, 29 March 2011 (2011-03-29), pages 3224 - 3231, XP055308975, Retrieved from the Internet [retrieved on 20230625], DOI: 10.1021/ac1032325
Attorney, Agent or Firm:
TEHRANCHI, Babak (US)
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