Title:
CANCER TREATMENT AGENT
Document Type and Number:
WIPO Patent Application WO/2018/074451
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a cancer treatment agent that is characterized by combining the active ingredient caffeine citrate with an anticancer agent which is an active ingredient. Specifically provided is a cancer treatment agent having the anticancer agent cisplatin, gemcitabine, or adriamycin as an active ingredient.
Inventors:
TSUCHIYA HIROYUKIO (JP)
TAKEUCHI AKIHIKO (JP)
ABE KENSAKU (JP)
YAMAMOTO NORIO (JP)
HAYASHI KATSUHIRO (JP)
TAKEUCHI AKIHIKO (JP)
ABE KENSAKU (JP)
YAMAMOTO NORIO (JP)
HAYASHI KATSUHIRO (JP)
Application Number:
PCT/JP2017/037473
Publication Date:
April 26, 2018
Filing Date:
October 17, 2017
Export Citation:
Assignee:
UNIV NAT CORP KANAZAWA (JP)
International Classes:
A61K31/522; A61K33/243; A61K45/00; A61P35/00
Foreign References:
| JP2012214465A | 2012-11-08 | |||
| JP2012515799A | 2012-07-12 | |||
| JP2015509788A | 2015-04-02 |
Other References:
TSUCHIYA HIROYUKI ET AL.: "Caffeine assisted Chemotherapy for soft Tissue Sarcoma", ISHIYAKU PUB INC., vol. 184, no. 5, 31 January 1998 (1998-01-31), pages 428 - 434
TAKAHASHI, MAKOTO ET AL.: "Combined effect of CDDP and caffeine against human gastric cell line in vivo", ANTICANCER RES, vol. 18, no. 6A, November 1998 (1998-11-01), pages 4399 - 4402, XP055604758
AL-SUKHUN, SANA ET AL.: "Chemoradiotherapy in the treatment of regional pancreatic carcinoma", AMERICAN JOURNAL OF CLINICAL ONCOLOGY, vol. 26, no. 6, December 2003 (2003-12-01), pages 543 - 549
LU , YAO-PING ET AL.: "Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 mice", CARCINOGENESIS, vol. 28, no. 1, 24 July 2006 (2006-07-24) - 1 January 2007 (2007-01-01), pages 199 - 206, XP055604765, ISSN: 0143-3334, DOI: 10.1093/carcin/bgl112
TAKAHASHI, MAKOTO ET AL.: "Combined effect of CDDP and caffeine against human gastric cell line in vivo", ANTICANCER RES, vol. 18, no. 6A, November 1998 (1998-11-01), pages 4399 - 4402, XP055604758
AL-SUKHUN, SANA ET AL.: "Chemoradiotherapy in the treatment of regional pancreatic carcinoma", AMERICAN JOURNAL OF CLINICAL ONCOLOGY, vol. 26, no. 6, December 2003 (2003-12-01), pages 543 - 549
LU , YAO-PING ET AL.: "Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 mice", CARCINOGENESIS, vol. 28, no. 1, 24 July 2006 (2006-07-24) - 1 January 2007 (2007-01-01), pages 199 - 206, XP055604765, ISSN: 0143-3334, DOI: 10.1093/carcin/bgl112
Attorney, Agent or Firm:
SHOJI, Takashi et al. (JP)
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