Title:
CANCEROUS DISEASE MODIFYING ANTIBODIES
Document Type and Number:
WIPO Patent Application WO2007095746
Kind Code:
A9
Abstract:
The present invention relates to a method for producing cancerous disease modifying antibodies using a novel paradigm of screening. By segregating lhe anti- cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, cytokines, interferons, target or reporter moieties and hematogenous cells.
Inventors:
YOUNG DAVID S F (CA)
FINDLAY HELEN P (CA)
HAHN SUSAN E (CA)
SAYEGH DAAD (CA)
FINDLAY HELEN P (CA)
HAHN SUSAN E (CA)
SAYEGH DAAD (CA)
Application Number:
PCT/CA2007/000279
Publication Date:
October 23, 2008
Filing Date:
February 22, 2007
Export Citation:
Assignee:
ARIUS RES INC (CA)
International Classes:
C12N5/16; A61K39/00; A61K39/395; A61K47/48; A61K51/10; A61P35/00; C07K16/18; C07K16/30; C12P21/08; G01N33/574; G01N33/577
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