Title:
CANINE CD20 COMPOSITIONS
Document Type and Number:
WIPO Patent Application WO2006007202
Kind Code:
A3
Abstract:
The invention provides canine CD20 nucleotide and protein sequences. These compositions are useful in the diagnosis and treatment of, e.g., CD20+ B-cell lymphoma, immune-mediated hemolytic anemia, immune-mediated thrombocytopenia, and systemic lupus erythematosus (SLE) in canines and felines.
Inventors:
BEALL MELISSA (US)
Application Number:
PCT/US2005/018515
Publication Date:
July 06, 2006
Filing Date:
May 26, 2005
Export Citation:
Assignee:
IDEXX LAB INC (US)
BEALL MELISSA (US)
BEALL MELISSA (US)
International Classes:
C07K14/705; C07K14/74; C07K16/28; C12N5/06; G01N33/50; G01N33/53; G01N33/564; G01N33/567
Foreign References:
| US5849898A | 1998-12-15 |
Other References:
COYLE K A ET AL: "Characterization of lymphocytes in canine gastrointestinal lymphoma.", VETERINARY PATHOLOGY. MAR 2004, vol. 41, no. 2, March 2004 (2004-03-01), pages 141 - 146, XP002377088, ISSN: 0300-9858
STAMENKOVIC I ET AL: "Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.", THE JOURNAL OF EXPERIMENTAL MEDICINE. 1 JUN 1988, vol. 167, no. 6, 1 June 1988 (1988-06-01), pages 1975 - 1980, XP009065525, ISSN: 0022-1007
RASTETTER W ET AL: "RITUXIMAB: EXPANDING ROLE IN THERAPY FOR LYMPHOMAS AND AUTOIMMUNE DISEASES", ANNUAL REVIEW OF MEDICINE : SELECTED TOPICS IN THE CLINICAL SCIENCES, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 55, 2004, pages 477 - 503, XP008060326, ISSN: 0066-4219
JUBALA C M ET AL: "CD20 expression in normal canine B cells and in canine non-Hodgkin lymphoma.", VETERINARY PATHOLOGY. JUL 2005, vol. 42, no. 4, July 2005 (2005-07-01), pages 468 - 476, XP009065299, ISSN: 0300-9858
KANO ET AL: "Canine CD20 gene", VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, AMSTERDAM, NL, vol. 108, no. 3-4, 15 December 2005 (2005-12-15), pages 265 - 268, XP005122097, ISSN: 0165-2427
See also references of EP 1751187A2
STAMENKOVIC I ET AL: "Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.", THE JOURNAL OF EXPERIMENTAL MEDICINE. 1 JUN 1988, vol. 167, no. 6, 1 June 1988 (1988-06-01), pages 1975 - 1980, XP009065525, ISSN: 0022-1007
RASTETTER W ET AL: "RITUXIMAB: EXPANDING ROLE IN THERAPY FOR LYMPHOMAS AND AUTOIMMUNE DISEASES", ANNUAL REVIEW OF MEDICINE : SELECTED TOPICS IN THE CLINICAL SCIENCES, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 55, 2004, pages 477 - 503, XP008060326, ISSN: 0066-4219
JUBALA C M ET AL: "CD20 expression in normal canine B cells and in canine non-Hodgkin lymphoma.", VETERINARY PATHOLOGY. JUL 2005, vol. 42, no. 4, July 2005 (2005-07-01), pages 468 - 476, XP009065299, ISSN: 0300-9858
KANO ET AL: "Canine CD20 gene", VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, AMSTERDAM, NL, vol. 108, no. 3-4, 15 December 2005 (2005-12-15), pages 265 - 268, XP005122097, ISSN: 0165-2427
See also references of EP 1751187A2
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