Title:
CANNABINOID RECEPTOR MODULATORS
Document Type and Number:
WIPO Patent Application WO/2013/005168
Kind Code:
A3
Abstract:
Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of cannabinoid (CB) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of cannabinoid (CB) receptors of Formula (I).
Inventors:
KULKARNI SANJEEV ANANT (IN)
MADAN SACHIN (IN)
JANA NIRMAL KUMAR (IN)
TALE PRASHANT VITTHALRAO (IN)
CHEEMALA NARASIMHA MURTHY (IN)
MAHANGARE SACHIN JAYSING (IN)
VIDHATE PRASHANT POPATRAO (IN)
KULKARNI CHAITANYA PRABHAKAR (IN)
PATEL SAPANA SURESH (IN)
PATIL AMOLSING DATTU (IN)
ZADE SEEMA PRABHAKAR (IN)
SHINDE ROHAN MAHADEV (IN)
PALLE VENKATA P (IN)
KAMBOJ RAJENDER KUMAR (IN)
MADAN SACHIN (IN)
JANA NIRMAL KUMAR (IN)
TALE PRASHANT VITTHALRAO (IN)
CHEEMALA NARASIMHA MURTHY (IN)
MAHANGARE SACHIN JAYSING (IN)
VIDHATE PRASHANT POPATRAO (IN)
KULKARNI CHAITANYA PRABHAKAR (IN)
PATEL SAPANA SURESH (IN)
PATIL AMOLSING DATTU (IN)
ZADE SEEMA PRABHAKAR (IN)
SHINDE ROHAN MAHADEV (IN)
PALLE VENKATA P (IN)
KAMBOJ RAJENDER KUMAR (IN)
Application Number:
PCT/IB2012/053407
Publication Date:
April 25, 2013
Filing Date:
July 04, 2012
Export Citation:
Assignee:
LUPIN LTD (IN)
KULKARNI SANJEEV ANANT (IN)
MADAN SACHIN (IN)
JANA NIRMAL KUMAR (IN)
TALE PRASHANT VITTHALRAO (IN)
CHEEMALA NARASIMHA MURTHY (IN)
MAHANGARE SACHIN JAYSING (IN)
VIDHATE PRASHANT POPATRAO (IN)
KULKARNI CHAITANYA PRABHAKAR (IN)
PATEL SAPANA SURESH (IN)
PATIL AMOLSING DATTU (IN)
ZADE SEEMA PRABHAKAR (IN)
SHINDE ROHAN MAHADEV (IN)
PALLE VENKATA P (IN)
KAMBOJ RAJENDER KUMAR (IN)
KULKARNI SANJEEV ANANT (IN)
MADAN SACHIN (IN)
JANA NIRMAL KUMAR (IN)
TALE PRASHANT VITTHALRAO (IN)
CHEEMALA NARASIMHA MURTHY (IN)
MAHANGARE SACHIN JAYSING (IN)
VIDHATE PRASHANT POPATRAO (IN)
KULKARNI CHAITANYA PRABHAKAR (IN)
PATEL SAPANA SURESH (IN)
PATIL AMOLSING DATTU (IN)
ZADE SEEMA PRABHAKAR (IN)
SHINDE ROHAN MAHADEV (IN)
PALLE VENKATA P (IN)
KAMBOJ RAJENDER KUMAR (IN)
International Classes:
A61K31/4725; A61K31/5377; A61K31/541; C07C237/48; C07D213/40; C07D217/14; C07D217/22; C07D217/26; C07D265/30; C07D309/04; C07D401/06; C07D405/12; C07D413/06; C07D471/08; C07D491/08
Domestic Patent References:
| WO2012090179A2 | 2012-07-05 | |||
| WO2012090177A2 | 2012-07-05 |
Foreign References:
| JP2012072068A | 2012-04-12 |
Other References:
SAARI RAIMO ET AL: "Microwave-assisted synthesis of quinoline, isoquinoline, quinoxaline and quinazoline derivatives as CB2 receptor agonists.", BIOORGANIC & MEDICINAL CHEMISTRY 15 JAN 2011 LNKD- PUBMED:21215643, vol. 19, no. 2, 9 December 2010 (2010-12-09), pages 939 - 950, XP002674004, ISSN: 1464-3391
PATEL K D ET AL: "Cannabinoid CB2 receptors in health and disease", CURRENT MEDICINAL CHEMISTRY 2010 BENTHAM SCIENCE PUBLISHERS B.V. NLD LNKD- DOI:10.2174/092986710790980041, vol. 17, no. 14, May 2010 (2010-05-01), pages 1394 - 1410, XP002674005, ISSN: 0929-8673
WORM K ET AL: "Simultaneous optimization of potency, selectivity and physicochemical properties for cannabinoid CB2 ligands", CURRENT PHARMACEUTICAL DESIGN 2009 BENTHAM SCIENCE PUBLISHERS B.V. NLD LNKD- DOI:10.2174/138161209789105027, vol. 15, no. 29, October 2009 (2009-10-01), pages 3345 - 3366, XP002674006, ISSN: 1381-6128
PATEL K D ET AL: "Cannabinoid CB2 receptors in health and disease", CURRENT MEDICINAL CHEMISTRY 2010 BENTHAM SCIENCE PUBLISHERS B.V. NLD LNKD- DOI:10.2174/092986710790980041, vol. 17, no. 14, May 2010 (2010-05-01), pages 1394 - 1410, XP002674005, ISSN: 0929-8673
WORM K ET AL: "Simultaneous optimization of potency, selectivity and physicochemical properties for cannabinoid CB2 ligands", CURRENT PHARMACEUTICAL DESIGN 2009 BENTHAM SCIENCE PUBLISHERS B.V. NLD LNKD- DOI:10.2174/138161209789105027, vol. 15, no. 29, October 2009 (2009-10-01), pages 3345 - 3366, XP002674006, ISSN: 1381-6128
Attorney, Agent or Firm:
MAJUMDAR, Subhatosh et al. (5 Harish Mukherjee Road, Kolkata 5, IN)
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