Title:
CAPSID PROTEIN ASSEMBLY INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/154343
Kind Code:
A1
Abstract:
The present invention relates to the field of pharmaceutical chemistry, and relates to a capsid protein assembly inhibitor, and in particular, to a compound represented by formula I, a stereoisomer, tautomer, solvate, hydrate, prodrug or pharmaceutically acceptable salt thereof, a preparation method thereof, a pharmaceutical composition thereof, and medical use thereof, comprising use in treating diseases benefiting from the capsid protein assembly inhibitor, and particularly, diseases caused by hepatitis B virus infection.
Inventors:
ZHANG YINSHENG (CN)
AO WANGWEI (CN)
SHEN HANGZHOU (CN)
LI YUAN (CN)
WANG HUI (CN)
NI JIE (CN)
ZHANG HUAN (CN)
GE XINGFENG (CN)
LU DANDAN (CN)
ZHANG YAQI (CN)
MA XUEQIN (CN)
SHI WEI (CN)
WANG XIAOJIN (CN)
XU HONGJIANG (CN)
AO WANGWEI (CN)
SHEN HANGZHOU (CN)
LI YUAN (CN)
WANG HUI (CN)
NI JIE (CN)
ZHANG HUAN (CN)
GE XINGFENG (CN)
LU DANDAN (CN)
ZHANG YAQI (CN)
MA XUEQIN (CN)
SHI WEI (CN)
WANG XIAOJIN (CN)
XU HONGJIANG (CN)
Application Number:
PCT/CN2019/074527
Publication Date:
August 15, 2019
Filing Date:
February 02, 2019
Export Citation:
Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
A61K31/00; C07D207/40; A61K31/401
Domestic Patent References:
| WO2015011281A1 | 2015-01-29 | |||
| WO2017156255A1 | 2017-09-14 |
Foreign References:
| CN105452220A | 2016-03-30 |
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LIMITED (CN)
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