Title:
CAPSULE FOR DRUG DELIVERY SYSTEMS OF TARGET TISSUE-SPECIFIC DELIVERY TYPE USING CARBOSILANE DENDRIMER
Document Type and Number:
WIPO Patent Application WO/2017/204337
Kind Code:
A1
Abstract:
The present invention relates to a targeting-type capsule for drug delivery systems.
The present invention addresses the problem of providing a capsule for drug delivery systems by utilizing the reactivity of a thiol with an alkyl halide, wherein the capsule comprises a silole-containing carbosilane dendrimer and a labeling protein containing a target recognition site (e.g., green fluorescent protein), can include a biological polymer or another molecule therein, and can deliver the biological polymer or the like selectively into a target cell.
Inventors:
SUZUKI MIHO (JP)
HATANO KEN (JP)
YOSHIDA SHOJIRO (JP)
YAMASHITA YASUHIRO (JP)
HATANO KEN (JP)
YOSHIDA SHOJIRO (JP)
YAMASHITA YASUHIRO (JP)
Application Number:
PCT/JP2017/019735
Publication Date:
November 30, 2017
Filing Date:
May 26, 2017
Export Citation:
Assignee:
UNIV SAITAMA (JP)
QUARRYMEN&CO INC (JP)
QUARRYMEN&CO INC (JP)
International Classes:
A61K47/42; A61K49/00; A61P29/00; A61P35/00; A61P37/00
Domestic Patent References:
| WO2016084979A1 | 2016-06-02 | |||
| WO2011050178A2 | 2011-04-28 | |||
| WO2005011632A1 | 2005-02-10 | |||
| WO2005011633A1 | 2005-02-10 | |||
| WO2016084979A1 | 2016-06-02 |
Foreign References:
| JP2011063587A | 2011-03-31 | |||
| JP2013506697A | 2013-02-28 | |||
| JP2010112777A | 2010-05-20 | |||
| JP2007001923A | 2007-01-11 | |||
| JP2009046413A | 2009-03-05 | |||
| JP2014073975A | 2014-04-24 | |||
| JP2001206885A | 2001-07-31 | |||
| JP2005120068A | 2005-05-12 | |||
| JP2007238860A | 2007-09-20 | |||
| JPS5629888B2 | 1981-07-11 |
Other References:
CHEM COMMUN (CAMB, no. 29, 13 May 2009 (2009-05-13), pages 4332 - 53
BIOCHEM. BIOPHYS. ACTA, vol. 1679, 2004, pages 222 - 229
BIOCHEM. BIOPHYS. RES. COMMUN., vol. 330, 2005, pages 454 - 460
TETRAHEDRON LETT., vol. 48, 2007, pages 4365 - 4368
BIOCHIM. BIOPHYS. ACTA, vol. 1679, 2004, pages 222 - 229
MIHO SUZUKI ET AL., BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - GENE STRUCTURE AND EXPRESSION, vol. 1679, no. 3, 17 September 2004 (2004-09-17), pages 222 - 229
See also references of EP 3476402A4
BIOCHEM. BIOPHYS. ACTA, vol. 1679, 2004, pages 222 - 229
BIOCHEM. BIOPHYS. RES. COMMUN., vol. 330, 2005, pages 454 - 460
TETRAHEDRON LETT., vol. 48, 2007, pages 4365 - 4368
BIOCHIM. BIOPHYS. ACTA, vol. 1679, 2004, pages 222 - 229
MIHO SUZUKI ET AL., BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - GENE STRUCTURE AND EXPRESSION, vol. 1679, no. 3, 17 September 2004 (2004-09-17), pages 222 - 229
See also references of EP 3476402A4
Attorney, Agent or Firm:
AYAFUNE INTERNATIONAL PATENTS & TRADEMARKS PATENT PROFESSIONAL CORPORATION (JP)
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