Title:
CAR-EXPRESSING PLURIPOTENT STEM CELL-DERIVED NEUTROPHILS LOADED WITH DRUG NANOPARTICLES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/245074
Kind Code:
A3
Abstract:
Chimeric antigen receptor (CAR)-expressing neutrophils loaded with nanoparticles comprising a drug; and a method of treating cancer or other disorders in a subject comprising administering to the subject a therapeutically effective amount of the CAR-expressing neutrophils.
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Inventors:
BAO XIAOPING (US)
DENG QING (US)
CHANG YUN (US)
DENG QING (US)
CHANG YUN (US)
Application Number:
PCT/US2023/068456
Publication Date:
January 25, 2024
Filing Date:
June 14, 2023
Export Citation:
Assignee:
PURDUE RESEARCH FOUNDATION (US)
International Classes:
C12N5/0787; C12N5/10
Domestic Patent References:
| WO2021152186A2 | 2021-08-05 |
Foreign References:
| US20210163895A1 | 2021-06-03 | |||
| US20170292113A1 | 2017-10-12 | |||
| US20210087295A1 | 2021-03-25 | |||
| US20130122056A1 | 2013-05-16 | |||
| US20220002675A1 | 2022-01-06 | |||
| US20190389917A1 | 2019-12-26 | |||
| US20170058029A1 | 2017-03-02 |
Attorney, Agent or Firm:
DEAN, Natalie, J. (US)
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