Title:
CARBIDOPA PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF FOR TREATING LIVER CANCER
Document Type and Number:
WIPO Patent Application WO/2017/215676
Kind Code:
A1
Abstract:
A carbidopa pharmaceutical composition and medical use thereof for treating liver cancer are provided. The carbidopa pharmaceutical composition provided in the present invention comprises carbidopa and a naturally produced compound (I) having a new structure and isolated from dry roots and stems of Notopterygium incisum. When used independently, carbidopa and the natural product has treatment effects on liver cancer. When the two are used in conjunction, the liver cancer treatment effects are further improved, which can be developed into medications for treating liver cancer.
Inventors:
CUI QUNFENG (CN)
Application Number:
PCT/CN2017/097011
Publication Date:
December 21, 2017
Filing Date:
August 11, 2017
Export Citation:
Assignee:
ZHAO JIYONG (CN)
International Classes:
C07D307/00; A61K31/198; A61K31/343; A61P1/16; A61P35/00
Domestic Patent References:
| WO2002020505A1 | 2002-03-14 | |||
| WO2012083953A1 | 2012-06-28 |
Foreign References:
| CN106083771A | 2016-11-09 | |||
| CN105777672A | 2016-07-20 | |||
| CN105801527A | 2016-07-27 | |||
| CN105820144A | 2016-08-03 | |||
| CN101190258A | 2008-06-04 | |||
| CN104628680A | 2015-05-20 |
Other References:
LAI, YONGJI ET AL.: "Scapiformolactones A-I: Germacrane Sesquiterpenoids with an Unusual DELTA3-15, 6-Lactone Moiety from Salvia Scapiformis", PHYTOCHEMISTRY, vol. 96, 1 November 2013 (2013-11-01), pages 378 - 388
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