Title:
CARBON MONOXIDE REMOVAL AGENT
Document Type and Number:
WIPO Patent Application WO/2010/098442
Kind Code:
A1
Abstract:
Disclosed is a carbon monoxide removal agent that can be easily administered to a patient by injection or orally. The carbon monoxide removal agent contains an inclusion complex, in which a cyclodextrin dimer represented by chemical formula (1) includes a water-soluble metalloporphyrin, as an active ingredient. (In the formula, m represents either of the numbers 1 or 2 and n represents any of the numbers 1, 2, or 3.)
Inventors:
KANO KOJI (JP)
KITAGISHI HIROAKI (JP)
NEGI SHIGERU (JP)
KIRIYAMA AKIKO (JP)
HONBO AKINO (JP)
KAWAGUCHI AKIRA (JP)
TSUKADA HIDEO (JP)
KITAGISHI HIROAKI (JP)
NEGI SHIGERU (JP)
KIRIYAMA AKIKO (JP)
HONBO AKINO (JP)
KAWAGUCHI AKIRA (JP)
TSUKADA HIDEO (JP)
Application Number:
PCT/JP2010/053072
Publication Date:
September 02, 2010
Filing Date:
February 26, 2010
Export Citation:
Assignee:
DOSHISHA (JP)
UNIV TOKAI EDUCATIONAL SYSTEM (JP)
HAMAMATSU PHOTONICS KK (JP)
KANO KOJI (JP)
KITAGISHI HIROAKI (JP)
NEGI SHIGERU (JP)
KIRIYAMA AKIKO (JP)
HONBO AKINO (JP)
KAWAGUCHI AKIRA (JP)
TSUKADA HIDEO (JP)
UNIV TOKAI EDUCATIONAL SYSTEM (JP)
HAMAMATSU PHOTONICS KK (JP)
KANO KOJI (JP)
KITAGISHI HIROAKI (JP)
NEGI SHIGERU (JP)
KIRIYAMA AKIKO (JP)
HONBO AKINO (JP)
KAWAGUCHI AKIRA (JP)
TSUKADA HIDEO (JP)
International Classes:
A61K31/714; A61K31/724; A61K47/40; A61P39/02; B01J20/22; C01B32/40
Foreign References:
| JP2006002077A | 2006-01-05 | |||
| JPS62135428A | 1987-06-18 | |||
| US5525630A | 1996-06-11 | |||
| JP2006002077A | 2006-01-05 |
Other References:
KANO, K. ET AL.: "Dioxygen Binding to a Simple Myoglobin Model in Aqueous Solution", ANGEW CHEM INT ED, vol. 44, no. 3, 2005, pages 435 - 438, XP055065921
KANO, K. ET AL.: "Iron Porphyrin-Cyclodextrin Supramolecular Complex as a Functional Model of Myoglobin in Aqueous Solution", INORG CHEM, vol. 45, no. 11, 2006, pages 4448 - 4460, XP055065922
TSUYOSHI KASHIMURA ET AL.: "New Application of Light Irradiation to the Treatment of Acute CO Poisoning", THE JAPANESE JOURNAL OF HYPERBARIC AND UNDERSEA MEDICINE, vol. 43, no. 4, 31 December 2008 (2008-12-31), pages 195 - 201, XP008166737
KITAGISHI, H. ET AL.: "A Diatomic Molecule Receptor That Removes CO in a Living Organism", ANGEW CHEM INT ED, vol. 49, no. 7, 8 February 2010 (2010-02-08), pages 1312 - 1315, XP055065920
See also references of EP 2402017A4
SATOSHI KITAMURA ET AL.: "Manual of Emergency Treatments and Prescriptions for Various Departments", 2005, ISHIYAKU PUBLISHING INC., pages: 547 - 549
KANO ET AL., ANGEW. CHEM. INT. ED., vol. 44, 2005, pages 435 - 438
K. KANO ET AL., INORG. CHEM., vol. 45, 2006, pages 4448 - 4460
S. AONO, ACC. CHEM. RES., vol. 36, 2003, pages 825 - 831
V. E. YUSHMANOV ET AL., MAG. RES. IMAGING, vol. 14, 1996, pages 255 - 261
T. T. TOMINAGA ET AL., J. INORG. BIOCHEM., vol. 65, 1997, pages 235 - 244
KANO, K. ET AL.: "Iron Porphyrin-Cyclodextrin Supramolecular Complex as a Functional Model of Myoglobin in Aqueous Solution", INORG CHEM, vol. 45, no. 11, 2006, pages 4448 - 4460, XP055065922
TSUYOSHI KASHIMURA ET AL.: "New Application of Light Irradiation to the Treatment of Acute CO Poisoning", THE JAPANESE JOURNAL OF HYPERBARIC AND UNDERSEA MEDICINE, vol. 43, no. 4, 31 December 2008 (2008-12-31), pages 195 - 201, XP008166737
KITAGISHI, H. ET AL.: "A Diatomic Molecule Receptor That Removes CO in a Living Organism", ANGEW CHEM INT ED, vol. 49, no. 7, 8 February 2010 (2010-02-08), pages 1312 - 1315, XP055065920
See also references of EP 2402017A4
SATOSHI KITAMURA ET AL.: "Manual of Emergency Treatments and Prescriptions for Various Departments", 2005, ISHIYAKU PUBLISHING INC., pages: 547 - 549
KANO ET AL., ANGEW. CHEM. INT. ED., vol. 44, 2005, pages 435 - 438
K. KANO ET AL., INORG. CHEM., vol. 45, 2006, pages 4448 - 4460
S. AONO, ACC. CHEM. RES., vol. 36, 2003, pages 825 - 831
V. E. YUSHMANOV ET AL., MAG. RES. IMAGING, vol. 14, 1996, pages 255 - 261
T. T. TOMINAGA ET AL., J. INORG. BIOCHEM., vol. 65, 1997, pages 235 - 244
Attorney, Agent or Firm:
SUGIMOTO KATSUNORI (JP)
Katsunori Sugimoto (JP)
Katsunori Sugimoto (JP)
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