CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME

Title:

CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME

Document Type and Number:

WIPO Patent Application WO/2001/025181

Kind Code:

A1

Abstract:

Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the derivatives as the active ingredient. In said formula, R?1¿ is hydrogen, hydroxyl, alkyl, or the like; L is a single bond, a double bond, alkylene, or the like; M is a single bond, alkylene, or the like; T is a single bond, alkylene, or the like; W is carboxyl, -CON(R?W1¿)R?W2¿, or the like; ...... represents a single or double bond; X is oxygen, alkenylene, or the like; Y is an aromatic hydrocarbon group which may contain a heteroatom, or the like; and Z is an aromatic hydrocarbon group which may contain a heteroatom.

Inventors:

SHINODA MASANOBU (JP)
EMORI EITA (JP)
MATSUURA FUMIYOSHI (JP)
KANEKO TOSHIHIKO (JP)
OHI NORIHITO (JP)
KASAI SHUNJI (JP)
YOSHITOMI HIDEKI (JP)
YAMAZAKI KAZUTO (JP)
MIYASHITA SADAKAZU (JP)
HIBARA TARO (JP)
SEIKI HISASHI (JP)
CLARK RICHARD (JP)
HARADA HITOSHI (JP)

Application Number:

PCT/JP2000/006788

Publication Date:

April 12, 2001

Filing Date:

September 29, 2000

Export Citation:

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Assignee:

EISAI CO LTD (JP)
SHINODA MASANOBU (JP)
EMORI EITA (JP)
MATSURA FUMIYOSHI (JP)
KANEKO TOSHIHIKO (JP)
OHI NORIHITO (JP)
KASAI SHUNJI (JP)
YOSHITOMI HIDEKI (JP)
YAMAZAKI KAZUTO (JP)
MIYASHITA SADAKAZU (JP)
HIBARA TARO (JP)
SEIKI HISASHI (JP)
CLARK RICHARD (JP)
HARADA HITOSHI (JP)

International Classes:

C07C59/66; C07C59/68; C07C233/51; C07C233/55; C07C233/87; C07C235/34; C07C235/38; C07C235/52; C07C235/60; C07C235/78; C07C235/84; C07C255/57; C07D209/14; C07D209/42; C07D213/30; C07D213/55; C07D213/56; C07D213/81; C07D213/82; C07D215/04; C07D217/26; C07D231/14; C07D233/90; C07D239/52; C07D241/24; C07D261/18; C07D263/26; C07D263/32; C07D277/20; C07D277/30; C07D277/34; C07D277/56; C07D307/54; C07D307/79; C07D333/24; C07D401/04; C07D417/04; C07D417/12; C07D417/14; (IPC1-7): C07C59/66; C07C69/734; C07C233/55; C07C233/87; C07C235/60; C07C235/78; C07C235/84; C07C271/22; C07D209/14; C07D263/32; C07D277/34; C07D263/26; C07D213/55; C07D417/12; C07D417/14; C07D307/54; C07D213/64; C07D307/78; C07D277/56; C07D417/04; C07D333/24; C07D333/28

Domestic Patent References:

WO1999020275A1	1999-04-29
WO1999019300A1	1999-04-22
WO1996031492A1	1996-10-10
WO1997036862A1	1997-10-09

Foreign References:

EP0763524A1	1997-03-19
EP0516069A1	1992-12-02
GB1436502A	1976-05-19
EP0911025A1	1999-04-28

Other References: