CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE

Title:

CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE

Document Type and Number:

WIPO Patent Application WO2006044415

Kind Code:

A3

Abstract:

Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.

Inventors:

SINGH JASBIR (US)
GURNEY MARK (US)
HATEGAN GEORGETA (US)
YU PENG (US)
ZEMBOWER DAVID (US)
ZHOU NIAN (US)
POLOZOV ALEXANDRE (US)
ZELLER WAYNE (US)

Application Number:

PCT/US2005/036574

Publication Date:

August 10, 2006

Filing Date:

October 11, 2005

Export Citation:

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Assignee:

DECODE CHEMISTRY INC (US)
SINGH JASBIR (US)
GURNEY MARK (US)
HATEGAN GEORGETA (US)
YU PENG (US)
ZEMBOWER DAVID (US)
ZHOU NIAN (US)
POLOZOV ALEXANDRE (US)
ZELLER WAYNE (US)

International Classes:

C07D487/04; A61K31/404; A61P9/10; C07D209/12; C07D209/34; C07D235/06; C07D263/58; C07D513/04

Foreign References:

EP1431267A1	2004-06-23
US5451688A	1995-09-19
DE911063C	1954-05-10

Other References:

THERIEN, M. ET AL.: "Synthesis and biological evaluation of 5,6-diarylimidazo(2.1b)thiazole as selective COX-2 inhibitors.", BIOORG. MED. CHEM. LETTERS, vol. 7, 1997, pages 47 - 52, XP002365681
WIEDENAU, P. ET AL.: "Total synthesis of (+)(-)-cis-trikentrin A", TETRAHEDRON, vol. 51, no. 4, 1995, pages 1167 - 1176, XP002365682
DATABASE BEILSTEIN 2000, KOCHERGIN, P.M. ET AL, XP002365685, Database accession no. 8708720,8709004
CONFALONE, P. ET AL.: "Stereospecific total synthesis of d-biotin from L-(+)-cysteine.", J. AM. CHEM. SOC., vol. 99, 1977, pages 7020 - 7026, XP002365683

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