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Patent Searching and Data


Title:
CARCINOGENESIS INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2018/230537
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a carcinogenesis inhibitor which has no side effects and exhibits excellent effects when orally administered. The carcinogenesis inhibitor according to the present invention, which comprises a hydantoin derivative or a pharmaceutically acceptable salt thereof as an active ingredient, exhibits effects of inhibiting polyp formation and inhibiting cell proliferation and has a high safety without posing side effects. Thus, the carcinogenesis inhibitor is highly useful in medicines and foods such as supplements for preventing the occurrence and progress of cancer, inhibiting the recurrence and metastasis of cancer and, furthermore, exerting therapeutic effects.

Inventors:
MUTO, Michihiro (5-1-1 Tsukiji Chuo-ku Tokyo, 45, 〒1040045, JP)
KUROKAWA, Yurie (5-1-1 Tsukiji Chuo-ku Tokyo, 45, 〒1040045, JP)
FUJII, Gen (5-1-1 Tsukiji Chuo-ku Tokyo, 45, 〒1040045, JP)
MIYAMOTO, Shingo (5-1-1 Tsukiji Chuo-ku Tokyo, 45, 〒1040045, JP)
Application Number:
JP2018/022333
Publication Date:
December 20, 2018
Filing Date:
June 12, 2018
Export Citation:
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Assignee:
NATIONAL CANCER CENTER JAPAN (5-1-1 Tsukiji, Chuo-ku Tokyo, 45, 〒1040045, JP)
NIPPON ZOKI PHARMACEUTICAL CO., LTD. (1-2 Hiranomachi 2-chome, Chuo-ku Osaka-sh, Osaka 46, 〒5410046, JP)
International Classes:
A61K31/4166; A23L33/10; A61P35/00; A61P43/00
Foreign References:
JPH09227377A1997-09-02
JP2002121132A2002-04-23
Other References:
KOKURA S. ET AL.: "Carcinogenesis due to Free Radicals and Carcinogenesis Preventive Effects of Ginkgo Leave Extracts", JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, vol. 38, 2006, pages 69 - 71
LEVO Y. ET AL.: "HYDANTOIN IMMUNOSUPPRESSION AMD CARCINOGENESIS", CLINICAL & EXPERIMENTAL IMMUNOLOGY, vol. 19, no. 3, 1975, pages 521 - 527
Attorney, Agent or Firm:
FUJII, Ikuro (NIPPON ZOKI PHARMACEUTICAL CO. LTD, Legal Management Division, 1-2, Hiranomachi 2-chome, Chuo-ku, Osaka-sh, Osaka 46, 〒5410046, JP)
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