Title:
CARDIAC DEVICE FOR ELECTRICAL AND CHEMICAL REGULATION, AND VASOACTIVE INTESTINAL PEPTIDE FOR TREATMENT OF CARDIOPULMONARY DISORDERS
Document Type and Number:
WIPO Patent Application WO2001034088
Kind Code:
A3
Abstract:
A method and device for discharging an electrical defibrillation pulse or an electrical demand pacer pulse or delivering at least one pharmaceutical agent to treat conditions such as cardiac arrest, bradycardia, arrhythmia, cardiac standstill, PEA, EMD and other heart conditions are disclosed. The pharmaceutical agent can be delivered into the heart tissue, the heart cavity, or the peritoneal cavity. The pharmaceutical agent can also include analgesics such as morphine. Also included are pharmaceutical agents used to increase myocardial contractility or inhibit platelet aggregation and vasoactive intestinal polypeptide (VIP) and thyroid hormones such as T3 and T4 can be delivered. A method for the treatment of cardiac arrest or pulmonary hypertension patients by administering a therapeutically effective amount of vasoactive intestinal polypeptide is also encompassed by the invention.
Inventors:
RUBIN LEO (US)
BERNSTEIN DAVID (US)
BERNSTEIN DAVID (US)
Application Number:
PCT/US2000/031348
Publication Date:
February 14, 2002
Filing Date:
November 13, 2000
Export Citation:
Assignee:
RUBIN LEO (US)
BERNSTEIN DAVID (US)
BERNSTEIN DAVID (US)
International Classes:
A61N1/39; A61K31/137; A61K31/167; A61K31/46; A61K33/00; A61K38/22; A61M25/00; A61N1/05; A61N1/362; A61P9/04; A61P9/10; A61P9/12; A61B17/00; A61M5/142; (IPC1-7): A61N1/18
Domestic Patent References:
| WO1998002453A2 | 1998-01-22 |
Foreign References:
| US5893881A | 1999-04-13 | |||
| US5269301A | 1993-12-14 | |||
| US6217886B1 | 2001-04-17 |
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