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Title:
CAROTENOID DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICALLY ACCEPTABLE ESTER OR AMIDE THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/178404
Kind Code:
A1
Abstract:
The present invention addresses the problem of discovering a carotenoid compound exhibiting excellent water solubility. Provided is a carotenoid derivative represented by general formula (I) [in general formula (I): X represents a carbonyl group or a methylene group; R1 and R2 represent (a), namely -CO-A-B-D (in (a), A represents an alkylene group, an alkenylene group, or the like, B represents the formula -S(O)n-, or the formula -NR4CONR5-, and D represents hydrogen, a carboxyl group, or the like), or (b), namely -CO-E-F (in (b), E represents an alkylene group, or the formula -NR3- {wherein R3 represents (a1) hydrogen, (b1) an alkyl group, or the like}, and F represents a sulfo group); and the remainder comprises hydrogen, (a), (b), or (c), namely -CO-G (in (c), G represents hydrogen, an alkyl group, or the like)]. Also provided are: a pharmaceutically acceptable salt of the carotenoid derivative; and a pharmaceutically acceptable ester or amide of the carotenoid derivative.

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Inventors:
FUJITA TAKASHI (JP)
KOBAYASHI SATOSHI (JP)
SHINOHARA RYOMA (JP)
NISHIDA YASUHIRO (JP)
TAKAHASHI JIRO (JP)
Application Number:
PCT/JP2015/064408
Publication Date:
November 26, 2015
Filing Date:
May 20, 2015
Export Citation:
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Assignee:
FUJI CHEM IND CO LTD (JP)
International Classes:
C07C403/24; A61K31/22; A61K31/27; A61K31/4178; A61P3/04; A61P3/06; A61P9/04; A61P9/12; A61P21/00; A61P25/18; A61P25/24; A61P25/28; A61P27/00; A61P27/02; A61P27/06; A61P29/00; A61P35/00; C07D233/61
Foreign References:
JP2013518856A2013-05-23
JP2010248243A2010-11-04
JP2007176814A2007-07-12
JP2006517197A2006-07-20
JP2005517010A2005-06-09
Other References:
See also references of EP 3147279A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
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