CARRIER COMPOUND FOR LIQUID PHASE SYNTHESIS OF POLYPEPTIDE, PREPARATION METHOD THEREFOR AND USE THEREOF

WIPO Patent Application WO/2019/127919

A1

The present invention relates to a carrier compound for liquid phase synthesis of a polypeptide, a preparation method therefor and use thereof, and specifically discloses a fused ring compound which can be used as a liquid phase carrier of the polypeptide. The fused ring compound is represented by formula (A) or (B), wherein X is selected from H, F, Cl, Br, I or a group bearing hydroxy, amino, carboxy, or halogen, and Y is selected from H, F, Cl, Br or I. The liquid phase synthesis carrier compound of the present invention is simple to prepare and has high reaction efficiency.

WO/2014/054410	INDENO[1,2-b]PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING THE SAME
WO/2013/109030	ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT COMPOUNDS
JP4510247	Hydrocarbon compounds and organic electroluminescent devices

YE SILEI (CN)
CHEN XINLIANG (CN)
MI PENGCHENG (CN)
TAO ANJIN (CN)
YUAN JIANCHENG (CN)

PCT/CN2018/079276

July 04, 2019

March 16, 2018

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HYBIO PHARMACEUTICAL CO LTD (CN)

C07C13/62; C07K7/16

CN101693738A	2010-04-14
CN105367627A	2016-03-02

LI, YONGZHEN ET AL.: "Progress in Synthesis and Applications of Polypeptides", CHEMISTRY & BIOENGINEERING, vol. 27, no. 4, 31 December 2010 (2010-12-31), pages 9 - 14
HAN, XIANG ET AL.: "Application of Solid-Phase Peptides Synthesis", PROGRESS IN PHARMACEUTICAL SCIENCES - OVERVIEW AND MONOGRAPH, vol. 28, no. 1, 31 December 2004 (2004-12-31), pages 10 - 14

BEIJING CHENGHUI LAW FIRM (CN)

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