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Title:
CARTILAGE REGENERATION-PROMOTING AGENT
Document Type and Number:
WIPO Patent Application WO/2013/164992
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a cartilage regeneration-promoting agent which is safe and can exhibit a cartilage regeneration-promoting effect when ingested on a daily basis; and a proteoglycan synthesis-promoting agent which can exhibit a proteoglycan synthesis-promoting effect when ingested. Provided are a cartilage regeneration-promoting agent and a proteoglycan synthesis-promoting agent, each of which comprises a milk-derived basic protein fraction as an active ingredient. When the milk-derived basic protein fraction is ingested orally, the synthesis of a proteoglycan and the regeneration of a cartilage can be promoted. A digestion product produced by hydrolyzing the milk-derived basic protein fraction also has a cartilage regeneration-promoting effect.

Inventors:
TAKANO, Yoshihiko (1-1, Naebocho 6-chome, Higashi-ku, Sapporo-sh, Hokkaido 43, 〒0650043, JP)
NARA, Takayuki (1-1, Naebocho 6-chome, Higashi-ku, Sapporo-sh, Hokkaido 43, 〒0650043, JP)
KATO, Ken (1-1, Naebocho 6-chome, Higashi-ku, Sapporo-sh, Hokkaido 43, 〒0650043, JP)
MORITA, Yoshikazu (1-1, Naebocho 6-chome, Higashi-ku, Sapporo-sh, Hokkaido 43, 〒0650043, JP)
Application Number:
JP2013/062525
Publication Date:
November 07, 2013
Filing Date:
April 30, 2013
Export Citation:
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Assignee:
MEGMILK SNOW BRAND CO., LTD. (1-1 Naebocho 6-chome, Higashi-ku Sapporo-sh, Hokkaido 43, 〒0650043, JP)
International Classes:
A61K38/00; A23K1/16; A23L1/30; A23L1/305; A61P19/02
Foreign References:
JPH08151331A1996-06-11
JP2010126461A2010-06-10
JP2007131548A2007-05-31
JP2006028071A2006-02-02
JPH05202098A1993-08-10
JPS61246198A1986-11-01
JPS6486839A1989-03-31
JPS63255300A1988-10-21
Other References:
YOSHIKAZU MORITA ET AL.: "Nyu Enkisei Tanpakushitsu (MBP) no Kotsuseicho ni Tomonau Nankotsu Saibo Kasseika Sayo", ANNUAL MEETING OF JSBBA KOEN YOSHISHU, vol. 2002, 5 March 2002 (2002-03-05), pages 105, XP008175449
See also references of EP 2851082A4
J. BIOL. CHEM., vol. 265, no. 10, 1990, pages 5903 - 5909
BIOCHEM. BIOPHYS. RES. COMMUN., vol. 301, no. 2, 2003, pages 338 - 343
BMC MUSCULOSKELET DISORD., 2004, pages 26
Attorney, Agent or Firm:
MOEGI PATENT OFFICE (7-7 Toranomon 2-chome, Minato-ku Tokyo, 01, 〒1050001, JP)
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