Title:
CASPASE-14 EXPRESSION INDUCER COMPOSED OF PHENYLETHYLAMINE DERIVATIVE OR SYNEPHRINE
Document Type and Number:
WIPO Patent Application WO/2015/045446
Kind Code:
A1
Abstract:
The objective of the present invention is to provide: a novel and useful caspase-14 expression inducer; and an external preparation for the skin containing a caspase-14 expression inducer. The present invention provides: a caspase-14 expression inducer which contains a phenylethylamine derivative or synephrine as an active ingredient; an external preparation for the skin containing a caspase-14 expression inducer. Since a phenylethylamine derivative or synephrine of the present invention has a caspase-14 expression inducing effect, the present invention is able to provide a moisturizing agent, a wetting agent and the like.
Inventors:
MASUTANI TERUAKI (JP)
ITO KENNICHI (JP)
KOJIMA HIROYUKI (JP)
ITO KENNICHI (JP)
KOJIMA HIROYUKI (JP)
Application Number:
PCT/JP2014/058188
Publication Date:
April 02, 2015
Filing Date:
March 25, 2014
Export Citation:
Assignee:
ICHIMARU PHARCOS INC (JP)
International Classes:
A61K8/41; A61K31/137; A61P17/00; A61P43/00; A61Q19/00
Foreign References:
| JP2001019607A | 2001-01-23 | |||
| JP2003524649A | 2003-08-19 | |||
| JP2004506677A | 2004-03-04 | |||
| JP2007106697A | 2007-04-26 | |||
| JP2013180970A | 2013-09-12 | |||
| JP2013184936A | 2013-09-19 |
Other References:
TERUAKI MASUTANI ET AL., ABSTRACTS OF THE 133RD ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN (YOKOHAMA, 30 March 2013 (2013-03-30), Retrieved from the Internet [retrieved on 20140611]
MICHIO SHIBATA ET AL.: "Research of sensitive skin and skin barrier for development of non- irritating skincare products", FRAGRANCE JOURNAL, August 2012 (2012-08-01), pages 16 - 20
HOSTE, ESTHER ET AL.: "Caspase-14 Is Required for Filaggrin Degradation to Natural Moisturizing Factors in the Skin", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 131, 2011, pages 2233 - 2241
MICHIO SHIBATA ET AL.: "Research of sensitive skin and skin barrier for development of non- irritating skincare products", FRAGRANCE JOURNAL, August 2012 (2012-08-01), pages 16 - 20
HOSTE, ESTHER ET AL.: "Caspase-14 Is Required for Filaggrin Degradation to Natural Moisturizing Factors in the Skin", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 131, 2011, pages 2233 - 2241
Download PDF:
Previous Patent: BIT CONNECTOR AND SCREW TIGHTENING DEVICE
Next Patent: ULTRASONIC TREATMENT TOOL AND SURGICAL SYSTEM
Next Patent: ULTRASONIC TREATMENT TOOL AND SURGICAL SYSTEM