Title:
CATALYST FOR ASYMMETRIC SYNTHESIS, LIGAND FOR USE THEREIN, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND THROUGH ASYMMETRIC SYNTHESIS REACTION USING THEM
Document Type and Number:
WIPO Patent Application WO/2006/088142
Kind Code:
A1
Abstract:
Compounds of the following general formula (1a) or (1b). (1a) (1b) Further, there are provided a complex comprising a central metal of rhodium and any of compounds of the general formula (1a) or (1b) as a ligand; comprised of this complex, a catalyst for optically active β-substituted carbonyl compound synthesis and catalyst for asymmetric 1,2 addition reaction; using these catalysts, a process for producing an optically active β-aryl compound from an &agr ,β-unsaturated compound and an arylboronic acid derivative and process for producing an optically active aryl alcohol compound from an aldehyde compound and an aryl boronic acid derivative; a complex comprising a central metal of palladium and any of compounds of the general formula (1a) or (1b) as a ligand; comprised of this complex, a catalyst for asymmetric allyl-position substitution reaction; and using this catalyst, a process for producing an optically active dialkyl (1,3-disubstituted propenyl)malonate compound from a 1,3-disubstituted allyl acetate compound and a dialkyl malonate and process for producing an optically active allylamine compound from a 1,3-disubstituted allyl acetate compound and an amine compound. The compounds have not only the versatility of being usable in the synthesis of wide-ranging optically active aryl compounds but also the selectivity and reactivity permitting synthesis with high yield within a short period of time under industrially advantageous mild conditions.
Inventors:
MIYAURA NORIO (JP)
YAMAMOTO YASUNORI (JP)
YAMAMOTO YASUNORI (JP)
Application Number:
PCT/JP2006/302850
Publication Date:
August 24, 2006
Filing Date:
February 17, 2006
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
MIYAURA NORIO (JP)
YAMAMOTO YASUNORI (JP)
MIYAURA NORIO (JP)
YAMAMOTO YASUNORI (JP)
International Classes:
C07F9/6574; B01J31/22; C07B53/00; C07C29/44; C07C33/34; C07C33/44; C07C45/70; C07C47/228; C07C49/213; C07C49/563; C07C49/657; C07C49/76; C07C67/24; C07C67/343; C07C69/612; C07C69/618; C07C209/16; C07C211/28; C07F15/00
Foreign References:
| JP2004315457A | 2004-11-11 | |||
| JP2004315396A | 2004-11-11 | |||
| US20040199023A1 | 2004-10-07 |
Other References:
BAHR A. ET AL.: "Dendritic, 1,1'-binaphthalene-derived cleft-type receptors (Dendroclefts) for the molecular recognition of pyranosides", HELVETICA CHIMICA ACTA, vol. 83, no. 7, 2000, pages 1346 - 1376, XP002999637
KOROSTYLEV A. ET AL.: "BINOL derived monodentate acylphosphite ligands for homogeneously catalyzed enantioselective hydrogenation", TETRAHEDRON: ASYMMETRY, vol. 15, no. 6, 22 March 2004 (2004-03-22), pages 1001 - 1005, XP004494499
J. ORG. CHEM., vol. 66, 2001, pages 8944
J. AM. CHEM. SOC., vol. 124, 2002, pages 5052
ANGEW. CHEM. INT. ED., vol. 37, 1998, pages 3279 - 3281
DIEGUEZ ET AL., NEW J. CHEM., vol. 26, no. 07, 2002, pages 827 - 833
KOROSTYLEV A. ET AL.: "BINOL derived monodentate acylphosphite ligands for homogeneously catalyzed enantioselective hydrogenation", TETRAHEDRON: ASYMMETRY, vol. 15, no. 6, 22 March 2004 (2004-03-22), pages 1001 - 1005, XP004494499
J. ORG. CHEM., vol. 66, 2001, pages 8944
J. AM. CHEM. SOC., vol. 124, 2002, pages 5052
ANGEW. CHEM. INT. ED., vol. 37, 1998, pages 3279 - 3281
DIEGUEZ ET AL., NEW J. CHEM., vol. 26, no. 07, 2002, pages 827 - 833
Attorney, Agent or Firm:
SIKs & Co. (Kyobashi-Nisshoku Bldg. 8-7, Kyobashi 1-chome, Chuo-k, Tokyo 31, JP)
Download PDF:
Previous Patent: PHTHALOCYANINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND COLORED COMPOSITION CONTAINING THE PHTH...
Next Patent: SHAFT DEVICE
Next Patent: SHAFT DEVICE