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Title:
CATIONIC LIPID
Document Type and Number:
WIPO Patent Application WO/2014/007398
Kind Code:
A1
Abstract:
Provided are: a cationic lipid represented by formula (A) or the like, which makes it easier to introduce a nucleic acid into, for example, a cell; a composition which contains the cationic lipid and a nucleic acid; a method for introducing a nucleic acid into a cell using the composition which contains the cationic lipid and the nucleic acid; and the like. (In the formula, R1 represents an alkenyl group or the like; R2 represents an alkenyl group or the like; each of R3 and R4 represents an alkyl group, or R3 and R4 combine together to form an alkylene group, or R3 may combine with R5 to form an alkylene group; R5 represents a hydrogen atom or the like, or may combine with R3 to form an alkylene group; X1 represents an alkylene group; and X2 represents a single bond or an alkylene group.)

Inventors:
KUBOYAMA TAKESHI (JP)
ERA TOMOHIRO (JP)
NAOI TOMOYUKI (JP)
YAGI KAORI (JP)
HOSOE SHINTARO (JP)
Application Number:
PCT/JP2013/068682
Publication Date:
January 09, 2014
Filing Date:
July 08, 2013
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KYOWA HAKKO KIRIN CO LTD (JP)
International Classes:
A61K31/7088; C07C271/12; A61K47/18; A61K47/44; A61K47/48; A61K48/00; A61P29/00; A61P35/00; C07C211/21; C07C215/08; C07C217/08; C07C271/16; C07D207/06; C07D207/08; C07D211/06; C07D211/22; C07D223/04; C07D225/02; C12N15/09; C12N15/113
Domestic Patent References:
WO2013089151A12013-06-20
WO2013089152A12013-06-20
WO2004039971A12004-05-13
WO2010042877A12010-04-15
WO2010054401A12010-05-14
WO2005089287A22005-09-29
WO1991016024A11991-10-31
WO1997019675A21997-06-05
WO2005121348A12005-12-22
WO2009086558A12009-07-09
WO2011136368A12011-11-03
WO2002028367A12002-04-11
WO2006080118A12006-08-03
WO2006116107A22006-11-02
WO2009129395A12009-10-22
Foreign References:
US20070213257A12007-09-13
JP2009203173A2009-09-10
JPH10509418A1998-09-14
JP2005532278A2005-10-27
JPS474599A
EP0407124A11991-01-09
JP2009501699A2009-01-22
US5049386A1991-09-17
JP2572554B21997-01-16
JP2659136B21997-09-30
JP2002508765A2002-03-19
JP2002501511A2002-01-15
Other References:
T.W. GREENE: "Protective Groups in Organic Synthesis", 1999, JOHN WILEY & SONS, INC.
"Dai 5-han Jikken Kagaku Kouza 13, Synthesis of Organic Compounds I", 2005, MARUZEN, pages: 374
"Dai 5-han, Jikken Kagaku Kouza 14, Synthesis of Organic Compounds II", 2005, MARUZEN, pages: 1
"Dai 5-han, Jikken Kagaku Kouza 14, Synthesis of Organic Compounds II", 2005, MARUZEN, pages: L
"Dai 5-han, Jikken Kagaku Kouza 13, Synthesis of Organic Compounds I", 2005, MARUZEN, pages: 374
"Dai 5-han, Jikken Kagaku Kouza 18, Synthesis of Organic Compounds VI", 2005, MARUZEN, pages: 171 - 172
JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 124, no. 10, 2002, pages 2092
NUCLEIC ACID RESEARCH, vol. 32, 2004, pages EL75
ACC. CHEM. RES., vol. 32, 1999, pages 624
J. AM. CHEM. SOC., vol. 123, 2001, pages 4653
J. AM. CHEM. SOC., vol. 122, 2000, pages 6900
BANGHAM ET AL., THE JOURNAL OF MOLECULAR BIOLOGY, vol. 13, 1965, pages 238 - 252
THE JOURNAL OF CELL BIOLOGY, vol. 66, 1975, pages 621 - 634
FEBS LETT., vol. 99, 1979, pages 210 - 214
THE ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 212, 1981, pages 186 - 194
THE PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 75, 1978, pages 4194 - 4198
BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1510, 2001, pages 152 - 166
"Stealth Liposomes", 1995, CRC PRESS INC., pages: 93 - 102
"Emulsion and Nanosuspensions for the Formulation of Poorly Soluble Drugs", 1998, SCIENTIFIC PUBLISHERS, pages: 267 - 294
JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 103, 1981, pages 4194 - 4199
See also references of EP 2871178A4
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