Title:
CD30-BINDING MOIETIES, CHIMERIC ANTIGEN RECEPTORS, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/135559
Kind Code:
A1
Abstract:
CD30-binding moieties, chimeric antigen receptors (CARs) having these CD30-binding moieties, and uses thereof are provided. Polynucleotides encoding the CD30-binding moieties and CARs, compositions comprising CD30-binding moieties and CARs,genetically modified immune cells having a chimeric antigen receptor for use in adoptive cell therapy for treating CD30-expressing cancer or tumor in a subject in need thereof are also provided herein.
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Inventors:
YANG SHUAI (CN)
WANG SUJUAN (CN)
SHU CHENYU (CN)
PENG YUANYUAN (CN)
HU CHEN (CN)
WU SHU (CN)
WANG SUJUAN (CN)
SHU CHENYU (CN)
PENG YUANYUAN (CN)
HU CHEN (CN)
WU SHU (CN)
Application Number:
PCT/CN2019/128613
Publication Date:
July 02, 2020
Filing Date:
December 26, 2019
Export Citation:
Assignee:
NANJING LEGEND BIOTECH CO LTD (CN)
International Classes:
C07K16/30; A61K35/14; A61K35/17; C07K14/705; C07K14/725; C07K16/28; C12N5/10
Domestic Patent References:
| WO2016008973A1 | 2016-01-21 | |||
| WO2018132695A1 | 2018-07-19 | |||
| WO2016154585A1 | 2016-09-29 | |||
| WO2015028444A1 | 2015-03-05 | |||
| WO2017144681A1 | 2017-08-31 | |||
| WO2003104432A2 | 2003-12-18 | |||
| WO2017210473A1 | 2017-12-07 |
Other References:
RAMOS, C.A . ET AL.: "Clinical and immunological responses after CD 30-specific chimeric antigen receptor-redirected lymphocytes", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 127, no. 9, 30 September 2017 (2017-09-30), pages 3462 - 3471, XP055722007
See also references of EP 3902838A4
See also references of EP 3902838A4
Attorney, Agent or Firm:
CHENG & PENG INTELLECTUAL PROPERTY LAW OFFICE (CN)
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