Title:
CD36 AS A HEAT SHOCK PROTEIN RECEPTOR AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2002036733
Kind Code:
A9
Abstract:
The present invention relates to the use of CD36 ("CD36") receptor as a heat shock protein receptor, cells that express CD36 bound to an HSP, and antibodies and other molecules that bind CD36-HSP complex. The invention also relates to screening assays to identify compounds that interact with CD36, and modulate the interaction of CD36 with its ligand, such as HSPs, and methods for using compositions comprising CD36-receptor sequences for the diagnosis and treatment of immune disorders, proliferative disorders, and infectious diseases.
Inventors:
PANJWANI NAVEED (US)
ZABRECKY JAMES (US)
ZABRECKY JAMES (US)
Application Number:
PCT/US2001/031401
Publication Date:
October 17, 2002
Filing Date:
October 05, 2001
Export Citation:
Assignee:
ANTIGENICS INC (US)
PANJWANI NAVEED (US)
ZABRECKY JAMES (US)
PANJWANI NAVEED (US)
ZABRECKY JAMES (US)
International Classes:
G01N33/50; A61K38/00; A61K39/395; A61K45/00; A61K48/00; A61P31/00; A61P35/00; A61P37/00; C07K14/47; C07K14/705; C12N5/10; C12N15/09; C12Q1/02; G01N33/15; G01N33/566; (IPC1-7): C12N/
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