Title:
CD47 ANTIGEN BINDING UNIT AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/137705
Kind Code:
A1
Abstract:
Disclosed herein are antigen binding units that specifically bind to CD47. Further disclosed herein are polynucleic acids encoding said antigen binding units, vectors comprising said polynucleic acids, and hybridomas and host cells comprising said vectors. Further provided herein are methods for inducing phagocytosis of CD47-expressing cells.
Inventors:
QIU YANGSHENG (CN)
LI JING (CN)
GAO HONGHAI (CN)
WU FENGLAN (CN)
FANG XU (CN)
LI SHOU (CN)
LU HONGTAO (CN)
YAN JAMES S (CN)
SHI LEI (CN)
LI JING (CN)
GAO HONGHAI (CN)
WU FENGLAN (CN)
FANG XU (CN)
LI SHOU (CN)
LU HONGTAO (CN)
YAN JAMES S (CN)
SHI LEI (CN)
Application Number:
PCT/CN2018/074318
Publication Date:
August 02, 2018
Filing Date:
January 26, 2018
Export Citation:
Assignee:
ZAI LAB SHANGHAI CO LTD (CN)
ZLIP HOLDING LTD (KY)
ZLIP HOLDING LTD (KY)
International Classes:
C07K16/18; A61K39/395; A61P35/00; A61P35/02; C07K19/00; C12N15/13; C12P21/08
Domestic Patent References:
| WO2013119714A1 | 2013-08-15 | |||
| WO2014093678A2 | 2014-06-19 | |||
| WO2014123580A1 | 2014-08-14 | |||
| WO2005044857A1 | 2005-05-19 |
Other References:
See also references of EP 3574009A4
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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