Title:
CELL CAPABLE OF REPLICATING NOVEL HCV REPLICON, CELL CAPABLE OF REPLICATING FULL-LENGTH HCV RNA, AND USE OF THOSE CELLS
Document Type and Number:
WIPO Patent Application WO/2010/026965
Kind Code:
A1
Abstract:
A cell capable of replicating an HCV replicon can be produced by employing a production method involving a step of introducing RNA containing an HCV replicon sequence and a selection marker gene sequence into a Li23 cell or a healing cell derived from a Li23 cell. A cell capable of replicating full-length HCV RNA can be produced by employing a production method involving a step of introducing RNA containing a full-length HCV genome sequence and a selection marker gene sequence into a cell presented by a Li23 cell or a healing cell derived from a Li23 cell. It becomes possible to construct an HCV life cycle reproduction system which is derived from a cell line other than HuH-7 cell line and has an ability equivalent to that of an HCV life cycle reproduction system derived from HuH-7 cell line.
Inventors:
KATO, Nobuyuki (())
加藤 宣之 (())
加藤 宣之 (())
Application Number:
JP2009/065263
Publication Date:
March 11, 2010
Filing Date:
September 01, 2009
Export Citation:
Assignee:
NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (1-1 Tsushima-naka 1-chome, Kita-ku Okayama-shi Okayama, 30, 〒7008530, JP)
国立大学法人岡山大学 (〒30 岡山県岡山市北区津島中一丁目１番１号 Okayama, 〒7008530, JP)
KATO, Nobuyuki (())
国立大学法人岡山大学 (〒30 岡山県岡山市北区津島中一丁目１番１号 Okayama, 〒7008530, JP)
KATO, Nobuyuki (())
International Classes:
C12N5/10; A61K45/00; A61P31/14; C12N7/00; C12N15/09; C12Q1/02; G01N33/15; G01N33/50
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (Daiwa Minamimorimachi Building, 2-6 Tenjinbashi 2-chome Kita,Kita-ku, Osaka-shi, Osaka 41, 〒5300041, JP)
Download PDF:
Previous Patent: SPOUT MEMBER AND PACKAGING BAG UTILIZING SAME
Next Patent: NOVEL ANTI-HCV AGENT AND USE THEREOF
Next Patent: NOVEL ANTI-HCV AGENT AND USE THEREOF