Title:
CELL CLASSIFICATION METHOD BASED ON LIGHT-INDUCED DIELECTROPHORESIS TECHNIQUE
Document Type and Number:
WIPO Patent Application WO/2017/028342
Kind Code:
A1
Abstract:
A cell classification method based on a light-induced dielectrophoresis technique, comprising: fabricating a light-induced dielectrophoresis chip composed of a three-layer structure; inputting a variable frequency alternating current signal to electrodes of upper and lower ITO glass layers of the light-induced dielectrophoresis chip, and using incident light to irradiate the light-induced dielectrophoresis chip; changing the frequency and magnitude of the alternating current signal so as to control a cell motion direction, and at the same time collecting an image of a cell; and performing fitting, according to the collected image, on the displacement of a cell to be classified and a time, and using, according to a fitting result, a trained support vector machine for classification so as to obtain a cell type. The classification method is low in cost, simple in operation and high in accuracy, being able to reach 97.5 percent of accuracy.
Inventors:
LI ZHI (CN)
ZHANG GUANGLIE (CN)
LI WEN JUNG (CN)
ZHANG GUANGLIE (CN)
LI WEN JUNG (CN)
Application Number:
PCT/CN2015/088946
Publication Date:
February 23, 2017
Filing Date:
September 06, 2015
Export Citation:
Assignee:
UNIV SHENZHEN (CN)
International Classes:
G01N27/447
Domestic Patent References:
| WO2015058265A1 | 2015-04-30 | |||
| WO2006025982A2 | 2006-03-09 |
Foreign References:
| CN102449163A | 2012-05-09 | |||
| CN101923648A | 2010-12-22 | |||
| CN101135680A | 2008-03-05 | |||
| CN1616958A | 2005-05-18 | |||
| CN1990093A | 2007-07-04 | |||
| US20140248621A1 | 2014-09-04 |
Attorney, Agent or Firm:
JOHNSON INTELLECTUAL PROPERTY AGENCY (SHENZHEN) (CN)
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