Title:
CELL CLUSTER, CELL STRUCTURE, AND THREE-DIMENSIONAL TISSUE BODY
Document Type and Number:
WIPO Patent Application WO/2017/131241
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a method for efficiently producing a cell cluster, cell structure, or three-dimensional tissue body using a culture surface coated with a temperature-responsive polymer or a temperature-responsive polymer composition. This method for producing a cell cluster, cell structure, or three-dimensional tissue body is characterized in that cells are seeded and cultivated on a culture surface coated with a temperature-responsive polymer or a temperature-responsive polymer composition.
Inventors:
NAKAYAMA YASUHIDE (JP)
IWAI RYOSUKE (JP)
NEMOTO YASUSHI (JP)
IWAI RYOSUKE (JP)
NEMOTO YASUSHI (JP)
Application Number:
PCT/JP2017/003879
Publication Date:
August 03, 2017
Filing Date:
January 27, 2017
Export Citation:
Assignee:
NAT CEREBRAL & CARDIOVASCULAR CT (JP)
BRIDGESTONE CORP (JP)
BRIDGESTONE CORP (JP)
International Classes:
C12N5/077; A61L27/36; C12M1/00; C12M3/00; C12N5/0775; C12N5/078; C12N5/0786; C12N5/0787
Domestic Patent References:
| WO2006093151A1 | 2006-09-08 | |||
| WO2004092359A1 | 2004-10-28 | |||
| WO2013005780A1 | 2013-01-10 | |||
| WO2015029707A1 | 2015-03-05 | |||
| WO2001068799A1 | 2001-09-20 | |||
| WO2013073707A1 | 2013-05-23 |
Foreign References:
| JP2014027918A | 2014-02-13 | |||
| JP2003010309A | 2003-01-14 | |||
| JP2015192640A | 2015-11-05 | |||
| JP2009050194A | 2009-03-12 | |||
| JP2010524458A | 2010-07-22 | |||
| JPS5746240B2 | 1982-10-01 | |||
| JP2014162865A | 2014-09-08 | |||
| JP2004261260A | 2004-09-24 |
Other References:
TOMONAGA T. ET AL.: "Rat hepatocyte spheroids formed on temperature-responsive PIPAAm polymer-grafted surface maintain long-term differentiated hepatocyte function", ACTA MEDICA NAGASAKI, vol. 59, no. 1, July 2014 (2014-07-01), pages 1 - 6, XP055519647
BRIDGESTONE CORP.: "Kigyo Booth Pamphlet,", PROCEEDINGS OF THE 32ND ANNUAL MEETING TOXICOLOGY / JUNE 29 - JULY 1, 2005, 29 June 2005 (2005-06-29), pages 1 - 6, XP009513613
RYOSUKE IWAI ET AL.: "One-Day-Aggregated Spheroids (ODAS) Gijutsu no Tenkai: Saisei Iryo Oyobi Soyaku Yoto o Shiko shita Saibo Spheroid no Sakusei", THE JOURNAL OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE SPECIAL EXTRA ISSUE, vol. 15, no. Suppl., 1 February 2016 (2016-02-01), pages 251, XP009513405
WANG Y. ET AL.: "Charge-selective fractions of naturally occurring nanoparticles as bioactive nanocarriers for cancer therapy", ACTA BIOMATERIALIA, vol. 10, no. 10, October 2014 (2014-10-01), pages 4269 - 4284, XP055519656
RYOSUKE IWAI ET AL.: "Jiko Soshikika Yudo Hyomen eno Dankaiteki Saibo Hashu ni yoru Kekkan'yo 2 So Kozotai no Sakusei", THE JOURNAL OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE SPECIAL EXTRA ISSUE, vol. 14, 1 February 2015 (2015-02-01), pages 203, XP009513411
YASUHIDE NAKAYAMA ET AL.: "Saibo o Atsumeru, Naraberu, Katachi ni suru, Kinoka dekiru Program-ka Baiyo Hyomen no Kaihatsu to Yuyosei", THE 14TH CONGRESS OF THE JAPANESE SOCIETY FOR REGENARATIVE MEDICINE, 19 March 2015 (2015-03-19), pages 1 - 7, XP009513416
M. MATSUSAKI ET AL., ADV. HEALTHCARE MATER., vol. 2, 2013, pages 534
M. MATSUSAKI ET AL., BIOCHEM. BIOPHYS. RES. COMMUN., vol. 457, 2015, pages 363
KELLER G. M. ET AL., CURR. OPIN. CELL BIOL., vol. 7, 1995, pages 862 - 869
NATURE, vol. 424, 21 August 2003 (2003-08-21), pages 870 - 872
BRIDGESTONE CORP.: "Kigyo Booth Pamphlet,", PROCEEDINGS OF THE 32ND ANNUAL MEETING TOXICOLOGY / JUNE 29 - JULY 1, 2005, 29 June 2005 (2005-06-29), pages 1 - 6, XP009513613
RYOSUKE IWAI ET AL.: "One-Day-Aggregated Spheroids (ODAS) Gijutsu no Tenkai: Saisei Iryo Oyobi Soyaku Yoto o Shiko shita Saibo Spheroid no Sakusei", THE JOURNAL OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE SPECIAL EXTRA ISSUE, vol. 15, no. Suppl., 1 February 2016 (2016-02-01), pages 251, XP009513405
WANG Y. ET AL.: "Charge-selective fractions of naturally occurring nanoparticles as bioactive nanocarriers for cancer therapy", ACTA BIOMATERIALIA, vol. 10, no. 10, October 2014 (2014-10-01), pages 4269 - 4284, XP055519656
RYOSUKE IWAI ET AL.: "Jiko Soshikika Yudo Hyomen eno Dankaiteki Saibo Hashu ni yoru Kekkan'yo 2 So Kozotai no Sakusei", THE JOURNAL OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE SPECIAL EXTRA ISSUE, vol. 14, 1 February 2015 (2015-02-01), pages 203, XP009513411
YASUHIDE NAKAYAMA ET AL.: "Saibo o Atsumeru, Naraberu, Katachi ni suru, Kinoka dekiru Program-ka Baiyo Hyomen no Kaihatsu to Yuyosei", THE 14TH CONGRESS OF THE JAPANESE SOCIETY FOR REGENARATIVE MEDICINE, 19 March 2015 (2015-03-19), pages 1 - 7, XP009513416
M. MATSUSAKI ET AL., ADV. HEALTHCARE MATER., vol. 2, 2013, pages 534
M. MATSUSAKI ET AL., BIOCHEM. BIOPHYS. RES. COMMUN., vol. 457, 2015, pages 363
KELLER G. M. ET AL., CURR. OPIN. CELL BIOL., vol. 7, 1995, pages 862 - 869
NATURE, vol. 424, 21 August 2003 (2003-08-21), pages 870 - 872
Attorney, Agent or Firm:
SUGIMURA, Kenji (JP)
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