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Title:
CELL DELIVERY DEVICE AND SYSTEM WITH ANTI-CLUMPING FEATURE AND METHODS FOR PELVIC TISSUE TREATMENT
Document Type and Number:
WIPO Patent Application WO/2014/078506
Kind Code:
A3
Abstract:
The invention is directed to cell delivery devices for providing a cell composition to a tissue or organ in the pelvic area for the treatment of a pelvic disorder. In some arrangements, the device has a cell delivery conduit that includes a turbulence-inducing feature that introduces sheer forces in the flow of liquid composition through the conduit, resulting in reduced cell clumping and improved single state cell delivery to the target tissue. In other arrangements, the device has a microfluidics channel which provides a similar effect for cell delivery. The resulting cell delivery can provide improved seeding of cells at the target tissue or organ and an improved therapeutic effect.

Inventors:
SCHROEDER TANIA M (US)
WATSCHKE BRIAN P (US)
MARKS ISAAC (US)
YONCE DAVID J (US)
Application Number:
PCT/US2013/070049
Publication Date:
July 10, 2014
Filing Date:
November 14, 2013
Export Citation:
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Assignee:
AMS RES CORP (US)
International Classes:
A61M5/32
Domestic Patent References:
WO2011091275A12011-07-28
Foreign References:
US5312356A1994-05-17
US20120101472A12012-04-26
US6629774B12003-10-07
US20090012497A12009-01-08
US6830563B12004-12-14
US6575930B12003-06-10
Other References:
REINDERS ET AL.: "Multipotent mesenchymal stromal cell therapy In renal disease and kidney transplantation", NEPHROL. DIAL. TRANSPLANT.., vol. 25, no. 1, 1 January 2010 (2010-01-01), pages 17 - 24, XP002662435
Attorney, Agent or Firm:
WEAVER, Paul, L. et al. (PLLCSuite 200, Maple Island Building,221 Main Street Nort, Stillwater MN, US)
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