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Title:
CELL DRUG-RESISTANCE TESTING METHOD BASED ON HIGH CONTENT IMAGING, AND MEDIUM AND ELECTRONIC DEVICE
Document Type and Number:
WIPO Patent Application WO/2022/111367
Kind Code:
A1
Abstract:
A cell drug-resistance testing method based on high content imaging, and a medium and an electronic device. The method comprises the following steps: performing fluorescence staining on a cell to be tested; performing high content imaging on the stained cell to be tested, and acquiring a corresponding high content image; pre-processing the high content image; and taking the pre-processed image as an input of a trained drug-resistance classification identification model based on a convolutional neural network, and detecting a drug-resistance category to which the cell to be tested belongs. Compared with the prior art, the method has the advantages of being simple, reliable and efficient.

Inventors:
HUANG GANG (CN)
LI XIUYING (CN)
NIE SHENGDONG (CN)
Application Number:
PCT/CN2021/131342
Publication Date:
June 02, 2022
Filing Date:
November 18, 2021
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Assignee:
SHANGHAI UNIV OF MEDICINE&HEALTH SCIENCES (CN)
UNIV OF SHANGHAI FOR SCIENCE AND TECHNOLOGY (CN)
International Classes:
G06K9/00
Foreign References:
CN112507821A2021-03-16
CN111260638A2020-06-09
CN111680575A2020-09-18
US20190065817A12019-02-28
Other References:
LI XIU-YING;HUANG GANG: "High-Content Imaging and Its Application in the Study of Cell Phenotype", JOURNAL OF CHINESE ELECTRON MICROSCOPY SOCIETY, vol. 39, no. 4, 15 August 2020 (2020-08-15), pages 451 - 455, XP055932652, ISSN: 1000-6281, DOI: 10.3969/j.issn.1000-6281.2020.04.017
Attorney, Agent or Firm:
SHANGHAI KESHENG INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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