Title:
CELL OBSERVATION APPARATUS
Document Type and Number:
WIPO Patent Application WO/2018/158946
Kind Code:
A1
Abstract:
The present invention is a cell observation apparatus whereby a two-dimensional distribution of phase information and intensity information is calculated on the basis of hologram data obtained by a holographic microscope, an image display field (120) in which two image display frames (121, 122) are provided being disposed in an image display screen image (100) displayed in a display unit. In the image display frames (121, 122), a phase image and an intensity image, respectively, corresponding to the same observation range are displayed on a cell culture plate (12) in which cells as an observation object are cultured. In the intensity image, a well on the plate that is almost invisible in the phase image can clearly be identified. By contrast, in the phase image, living cells that are almost invisible in the intensity image can be observed. An observer therefore determines a range to be observed in a well in the intensity image, and magnifies the determined range and observes cells in detail in the phase image. Cells that are present in the range to be observed in a well can thereby be positively observed.
Inventors:
AOI YUSUKE (JP)
KIMURA KATSUTOSHI (JP)
KIMURA KATSUTOSHI (JP)
Application Number:
PCT/JP2017/008567
Publication Date:
September 07, 2018
Filing Date:
March 03, 2017
Export Citation:
Assignee:
SHIMADZU CORP (JP)
International Classes:
G01N21/41; C12M1/34; G02B21/00; G03H1/00
Domestic Patent References:
| WO2013070287A1 | 2013-05-16 | |||
| WO2011089908A1 | 2011-07-28 |
Foreign References:
| JP2013508775A | 2013-03-07 | |||
| US9025881B2 | 2015-05-05 |
Attorney, Agent or Firm:
KYOTO INTERNATIONAL PATENT LAW OFFICE (JP)
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