Title:
CELL PEELING DEVICE AND CELL PEELING METHOD
Document Type and Number:
WIPO Patent Application WO/2023/079905
Kind Code:
A1
Abstract:
Provided is a cell peeling device that can efficiently peel cells that have uneven adhesion due to cell culturing conditions, peeling same in a non-contact manner from a culture container. This cell peeling device (10) peels cells (1) from a culture container (2) to which the cells (1) are adhered and comprises: an ultrasonic probe (12) that has a plurality of piezoelectric elements (11) that generate ultrasonic waves and form ultrasonic beams (20); a travel mechanism (14) that moves the ultrasonic probe (12) and enables the relative position of the ultrasonic probe (12) and the culture container (2) to be changed; a voltage application unit (13) that provides a delay and applies voltage to the plurality of piezoelectric elements (11); a cell state detection unit (18) that detects the cell state inside the culture container (2); and a peeling planning unit (30) that refers to the cell state obtained from the cell state detection unit (18) and determines the transmission conditions for the ultrasonic beams (20).
Inventors:
SASAKI KOTA (JP)
SUZUKI MUTSUMI (JP)
KOURAI YUUSUKE (JP)
MIZOTA HIROHISA (JP)
SUZUKI MUTSUMI (JP)
KOURAI YUUSUKE (JP)
MIZOTA HIROHISA (JP)
Application Number:
PCT/JP2022/037730
Publication Date:
May 11, 2023
Filing Date:
October 07, 2022
Export Citation:
Assignee:
HITACHI LTD (JP)
International Classes:
C12M1/42; C12M1/00; C12M1/26; C12N13/00
Domestic Patent References:
| WO2014017481A1 | 2014-01-30 | |||
| WO2016136365A1 | 2016-09-01 |
Foreign References:
| JP2015505472A | 2015-02-23 | |||
| JP2009000444A | 2009-01-08 | |||
| JP2008200155A | 2008-09-04 | |||
| JP2016158724A | 2016-09-05 |
Attorney, Agent or Firm:
ISONO INTERNATIONAL PATENT OFFICE, P.C. (JP)
Download PDF: