Title:
CELL PRODUCTION DEVICE
Document Type and Number:
WIPO Patent Application WO/2019/187618
Kind Code:
A1
Abstract:
One embodiment of the present invention is a cell production device having a cell nucleus for a first cell and including a cell membrane for the first cell and a cell membrane for the second cell. The cell production device comprises: a first flow path and a second flow path; a hole provided between a wall in the first flow path and a wall in the second flow path and penetrating the first flow path and the second flow path; an electrode provided sandwiching the hole; a DC/AC signal generation device for applying voltage to the hole; a third flow path connected to the first flow path via an opening and parallel to the first flow path; a cell recovery unit connected to an end on the opposite side to the opening in the third flow path; and a pillar provided inside the first flow path and the second flow path.
Inventors:
OKANOJO MASAHIRO (JP)
TAKEDA SHIZU (JP)
OKEYO KENNEDY OMONDI (JP)
WASHIZU MASAO (JP)
TAKEDA SHIZU (JP)
OKEYO KENNEDY OMONDI (JP)
WASHIZU MASAO (JP)
Application Number:
PCT/JP2019/003580
Publication Date:
October 03, 2019
Filing Date:
February 01, 2019
Export Citation:
Assignee:
HITACHI LTD (JP)
UNIV TOKYO (JP)
UNIV TOKYO (JP)
International Classes:
C12M1/00; C12M1/42; C12N15/02
Foreign References:
| JP2015506674A | 2015-03-05 | |||
| JP2008538283A | 2008-10-23 | |||
| JP2018148809A | 2018-09-27 |
Other References:
OKANOJO, MASAHIRO ET AL.: "Cellular Nuclear Exchange Based on Cell Fusion with Electric Field Concentration for Cell Reprogramming", THE ANNUAL MEETING RECORD, I.E.E. JAPAN, vol. 29, 2017, pages 173 - 174
YAMADA, MASUMI ET AL., MICRO-FLUID DEVICES FOR CELL SEPARATION/SELECTION, vol. 92, 2014, pages 153 - 156
OKANOJO, MASAHIRO ET AL.: "Development of cellular nuclear exchange method based on cell fusion with electric field concentration for cell reprogramming", THE PROCEEDINGS OF THE 30TH BIOENGINEERING CONFERENCE ANNUAL MEETING OF BED/JSME, 2017, pages 238
YAMADA, MASUMI ET AL., MICRO-FLUID DEVICES FOR CELL SEPARATION/SELECTION, vol. 92, 2014, pages 153 - 156
OKANOJO, MASAHIRO ET AL.: "Development of cellular nuclear exchange method based on cell fusion with electric field concentration for cell reprogramming", THE PROCEEDINGS OF THE 30TH BIOENGINEERING CONFERENCE ANNUAL MEETING OF BED/JSME, 2017, pages 238
Attorney, Agent or Firm:
ISSHIKI & CO. (JP)
Download PDF: