Title:
CELL-SEALING DEVICE
Document Type and Number:
WIPO Patent Application WO/2018/230588
Kind Code:
A1
Abstract:
As a cell-sealing device with which it is possible to seal a larger cell mass due to sufficient oxygen being supplied to cells in an implant part, there is provided a cell-sealing device in which a plurality of capsule-form structures, in which at least part of an outer shell is formed from an oxygen-permeable membrane and which have cells sealed therein, is arrayed in two-dimensional directions on the same plane.
Inventors:
IWATA HIROO (JP)
Application Number:
PCT/JP2018/022509
Publication Date:
December 20, 2018
Filing Date:
June 13, 2018
Export Citation:
Assignee:
TAKEDA PHARMACEUTICALS CO (JP)
International Classes:
C12M1/00; A61F2/02; A61L27/14; A61L27/20; A61L27/28; A61L27/38; A61L27/40; A61L27/50; A61L27/52; A61L27/54; A61L27/56; A61K9/50; A61K9/52; A61K35/12; A61K35/28; A61K35/39; A61K47/30; A61L27/34; A61P5/50; A61P43/00
Domestic Patent References:
| WO2017073625A1 | 2017-05-04 | |||
| WO2007069666A1 | 2007-06-21 | |||
| WO2008118220A2 | 2008-10-02 | |||
| WO2008124133A1 | 2008-10-16 | |||
| WO2008151058A2 | 2008-12-11 | |||
| WO2009006930A1 | 2009-01-15 | |||
| WO2009006997A1 | 2009-01-15 | |||
| WO2009007852A2 | 2009-01-15 |
Foreign References:
| JP2014159477A | 2014-09-04 | |||
| JP2016516827A | 2016-06-09 | |||
| JP2012172055A | 2012-09-10 | |||
| JPH08507949A | 1996-08-27 | |||
| JP2012508584A | 2012-04-12 | |||
| JP2016512022A | 2016-04-25 | |||
| JP2008307007A | 2008-12-25 | |||
| JP2008283972A | 2008-11-27 | |||
| US20080233610A1 | 2008-09-25 | |||
| US20090047263A1 | 2009-02-19 |
Other References:
LEE, B. R. ET AL.: "In situ formation and collagen- alginate composite encapsulation of pancreatic islet spheroids", BIOMATERIALS, vol. 33, no. 3, 3 November 2011 (2011-11-03), pages 837 - 845, XP055368475, Retrieved from the Internet
PARK, Y. G. ET AL.: "Microencapsulation of islets and model beads with a thin alginate-Ba2+ gel layer using centrifugation", POLYMERS FOR ADVANCED TECHNOLOGIES, vol. 9, no. 10-11, 4 December 1998 (1998-12-04), pages 734 - 739, XP055563267, Retrieved from the Internet3.0.CO;2-J>
JIANG, L. Y. ET AL.: "Investigating design principles of micropatterned encapsulation systems containing high-density microtissue arrays", SCIENCE CHINA LIFE SCIENCES, vol. 57, no. 2, 16 January 2014 (2014-01-16), pages 221 - 231, XP035710892, Retrieved from the Internet
KANG, A . ET AL.: "Cell encapsulation via microtechnologies", BIOMATERIALS, vol. 35, no. 9, 15 January 2014 (2014-01-15), pages 2651 - 2663, XP028829045, Retrieved from the Internet
OHGAWARA H: "Membrane immunoisolation of a diffusion chamber for bioartificial pancreas", ARTIF. ORGANS, vol. 22, no. 9, 1998, pages 788 - 94
REZANIA A: "Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells", NAT. BIOTECHNOL., vol. 32, no. 11, 2014, pages 1121 - 33, XP055200937, DOI: 10.1038/nbt.3033
IWATA H: "Agarose for a bioartificial pancreas", J. BIOMED. MATER. RES., vol. 26, no. 7, 1992, pages 967 - 77, XP001012761, DOI: 10.1002/jbm.820260711
TAKAHASHI KYAMANAKA S., CELL, vol. 126, 2006, pages 663 - 676
TAKAHASHI KYAMANAKA S. ET AL., CELL, vol. 131, 2007, pages 861 - 872
OKITA, K.ICHISAKA, T.YAMANAKA, S., NATURE, vol. 451, 2007, pages 141 - 146
HUANGFU D.MELTON, DA. ET AL., NATURE BIOTECHNOLOGY, vol. 26, no. 7, 2008, pages 795 - 797
OKITA K ET AL., NAT. METHODS, vol. 8, no. 5, May 2011 (2011-05-01), pages 409 - 12
OKITA K ET AL., STEM CELLS, vol. 31, no. 3, pages 458 - 66
YU J.THOMSON JA. ET AL., SCIENCE, vol. 318, 2007, pages 1917 - 1920
SHI Y.DING S. ET AL., CELL STEM CELL, vol. 3, no. 5, 2008, pages 568 - 574
KIM JB.SCHOLER HR. ET AL., NATURE, vol. 454, 2008, pages 646 - 650
VASILEIOS KARANTALISJOSHUA M. HARE, CIRC RES., vol. 116, no. 8, 10 April 2015 (2015-04-10), pages 1413 - 1430
IMRAN ULLAH ET AL., BIOSCI. REP., vol. 35, 2015, pages e00191
See also references of EP 3640318A4
PARK, Y. G. ET AL.: "Microencapsulation of islets and model beads with a thin alginate-Ba2+ gel layer using centrifugation", POLYMERS FOR ADVANCED TECHNOLOGIES, vol. 9, no. 10-11, 4 December 1998 (1998-12-04), pages 734 - 739, XP055563267, Retrieved from the Internet
JIANG, L. Y. ET AL.: "Investigating design principles of micropatterned encapsulation systems containing high-density microtissue arrays", SCIENCE CHINA LIFE SCIENCES, vol. 57, no. 2, 16 January 2014 (2014-01-16), pages 221 - 231, XP035710892, Retrieved from the Internet
KANG, A . ET AL.: "Cell encapsulation via microtechnologies", BIOMATERIALS, vol. 35, no. 9, 15 January 2014 (2014-01-15), pages 2651 - 2663, XP028829045, Retrieved from the Internet
OHGAWARA H: "Membrane immunoisolation of a diffusion chamber for bioartificial pancreas", ARTIF. ORGANS, vol. 22, no. 9, 1998, pages 788 - 94
REZANIA A: "Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells", NAT. BIOTECHNOL., vol. 32, no. 11, 2014, pages 1121 - 33, XP055200937, DOI: 10.1038/nbt.3033
IWATA H: "Agarose for a bioartificial pancreas", J. BIOMED. MATER. RES., vol. 26, no. 7, 1992, pages 967 - 77, XP001012761, DOI: 10.1002/jbm.820260711
TAKAHASHI KYAMANAKA S., CELL, vol. 126, 2006, pages 663 - 676
TAKAHASHI KYAMANAKA S. ET AL., CELL, vol. 131, 2007, pages 861 - 872
OKITA, K.ICHISAKA, T.YAMANAKA, S., NATURE, vol. 451, 2007, pages 141 - 146
HUANGFU D.MELTON, DA. ET AL., NATURE BIOTECHNOLOGY, vol. 26, no. 7, 2008, pages 795 - 797
OKITA K ET AL., NAT. METHODS, vol. 8, no. 5, May 2011 (2011-05-01), pages 409 - 12
OKITA K ET AL., STEM CELLS, vol. 31, no. 3, pages 458 - 66
YU J.THOMSON JA. ET AL., SCIENCE, vol. 318, 2007, pages 1917 - 1920
SHI Y.DING S. ET AL., CELL STEM CELL, vol. 3, no. 5, 2008, pages 568 - 574
KIM JB.SCHOLER HR. ET AL., NATURE, vol. 454, 2008, pages 646 - 650
VASILEIOS KARANTALISJOSHUA M. HARE, CIRC RES., vol. 116, no. 8, 10 April 2015 (2015-04-10), pages 1413 - 1430
IMRAN ULLAH ET AL., BIOSCI. REP., vol. 35, 2015, pages e00191
See also references of EP 3640318A4
Attorney, Agent or Firm:
OHNO Seiji et al. (JP)
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