Title:
CELL SEPARATION MATERIAL AND CELL SEPARATION METHOD
Document Type and Number:
WIPO Patent Application WO/2016/047444
Kind Code:
A1
Abstract:
The present invention pertains to: a cell separation material comprising fibers having an average fiber diameter of 1.0-50 µm, air permeability of 10-400 cc/cm2/sec, and a compression energy WC of no more than 3.5 J/m2; a cell separation filter characterized by having several layers of the cell separation material laminated and filled into a container having an entry and an exit; and a cell separation method including a step in which fluid including rare cells is caused to pass through the cell separation filter and fractions rich in rare cells are captured in the cell separation material. As a result of the present invention, rare cells can be selectively recovered, at a high recovery rate, from a fluid having mixed therein rare cells such as circulating tumor cells and contaminating cells such as red blood cells, platelets, platelets, and leukocytes.
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Inventors:
YAMAMOTO AYUMI (JP)
MIZOKAMI YASUHIRO (JP)
MIZOKAMI YASUHIRO (JP)
Application Number:
PCT/JP2015/075602
Publication Date:
March 31, 2016
Filing Date:
September 09, 2015
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
C12M1/12; A61M1/16; A61M1/34; B01D39/16; C12N1/02; C12N5/078
Domestic Patent References:
| WO2007046501A1 | 2007-04-26 |
Foreign References:
| JP2013036818A | 2013-02-21 | |||
| JP2011010582A | 2011-01-20 | |||
| JP2011010581A | 2011-01-20 |
Other References:
HOU S. ET AL.: "Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures.", ADV. MATER., vol. 25, no. 11, 2013, pages 1547 - 1551, XP008176461
Attorney, Agent or Firm:
YANAGINO Takao et al. (JP)
Takao Yanagino (JP)
Takao Yanagino (JP)
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