Title:
CELL TRANSPORT
Document Type and Number:
WIPO Patent Application WO/2015/063452
Kind Code:
A3
Abstract:
The invention relates to novel polypeptides for transporting molecules across cell membranes and, particularly but not exclusively, biological membranes; a conjugate comprising at least one of said polypeptides and at least one selected molecule or agent co-joined or conjugated to said polypeptide for the purpose of transporting said molecule or agent across a cell membrane; a method of transporting at least one selected molecule or agent across a cell membrane involving the use of at least one of said polypeptides; a therapeutic comprising at least one of said conjugates; a combination therapeutic comprising at least one of said conjugates and at least one further therapeutic agent; a method of treatment involving the use of at least one of said conjugates or said therapeutics.
Inventors:
RYVES WILLIAM JONATHAN (GB)
Application Number:
PCT/GB2014/053037
Publication Date:
September 17, 2015
Filing Date:
October 09, 2014
Export Citation:
Assignee:
CUPID PEPTIDE COMPANY LTD (GB)
International Classes:
A61K47/48; C07K7/08; C12N15/62; C12N15/87
Domestic Patent References:
| WO2005016387A2 | 2005-02-24 | |||
| WO2002072807A2 | 2002-09-19 |
Other References:
W JONATHAN RYVES ET AL: "Penetratin in Dictyostelium 123 MOLECULAR BIOTECHNOLOGY Use of a Penetratin-Linked Peptide in Dictyostelium", 1 January 2006 (2006-01-01), XP055161179, Retrieved from the Internet [retrieved on 20150112]
"Dictyostelium purpureum (Slime mold)", INTERNET CITATION, 1 June 2011 (2011-06-01), pages 1 - 3, XP007922960, Retrieved from the Internet [retrieved on 20150119]
VOLKER JÄGER ET AL: "High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells", BMC BIOTECHNOLOGY, BIOMED CENTRAL LTD. LONDON, GB, vol. 13, no. 1, 26 June 2013 (2013-06-26), pages 52, XP021155277, ISSN: 1472-6750, DOI: 10.1186/1472-6750-13-52
WURM F M: "Production of recombinant protein therapeutics in cultivated mammalian cells", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 22, no. 11, 1 November 2004 (2004-11-01), pages 1393 - 1398, XP002667427, ISSN: 1087-0156, [retrieved on 20041104], DOI: 10.1038/NBT1026
"Dictyostelium purpureum (Slime mold)", INTERNET CITATION, 1 June 2011 (2011-06-01), pages 1 - 3, XP007922960, Retrieved from the Internet
VOLKER JÄGER ET AL: "High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells", BMC BIOTECHNOLOGY, BIOMED CENTRAL LTD. LONDON, GB, vol. 13, no. 1, 26 June 2013 (2013-06-26), pages 52, XP021155277, ISSN: 1472-6750, DOI: 10.1186/1472-6750-13-52
WURM F M: "Production of recombinant protein therapeutics in cultivated mammalian cells", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 22, no. 11, 1 November 2004 (2004-11-01), pages 1393 - 1398, XP002667427, ISSN: 1087-0156, [retrieved on 20041104], DOI: 10.1038/NBT1026
Attorney, Agent or Firm:
SYMBIOSIS IP LIMITED (Vale Business ParkCrab Apple Way,Evesham, Worcestershire WR11 1GP, GB)
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