Title:
CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF
Document Type and Number:
WIPO Patent Application WO/1991/006549
Kind Code:
A1
Abstract:
Cephalosporin compounds represented by general formula (I), pharmacologically acceptable addition salts thereof, method for the production thereof, and medicinal uses thereof, wherein R1 represents hydrogen or lower alkyl, and R2 represents 1-alkanoyloxyalkyl or 1-alkoxycarbonyloxy-alkyl. These compounds and salts not only can be readily absorbed through the digestive tract to exhibit wide antibacterial activities in vivo in the form of the hydrolyzates thereof, but also have remarkable sweetness 10 to 400 times as high as that of sucrose. Therefore they are useful in preventing and treating infectious diseases by oral administration.
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Inventors:
MURO HIROYUKI (JP)
KASAI MASAYASU (JP)
HATANO SATORU (JP)
NISHIMURA KEN-ICHI (JP)
NISHIZAWA SUSUMU (JP)
KAKEYA NOBUHARU (JP)
KASAI MASAYASU (JP)
HATANO SATORU (JP)
NISHIMURA KEN-ICHI (JP)
NISHIZAWA SUSUMU (JP)
KAKEYA NOBUHARU (JP)
Application Number:
PCT/JP1990/001370
Publication Date:
May 16, 1991
Filing Date:
October 24, 1990
Export Citation:
Assignee:
KYOTO PHARMA IND (JP)
International Classes:
A61K31/545; A61K31/546; A61P31/04; C07D501/00; C07D501/20; C07D501/22; (IPC1-7): A61K31/545; C07D501/20
Foreign References:
| JPS58180491A | 1983-10-21 |
Other References:
See also references of EP 0497978A4
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