CEPHEM COMPOUND HAVING CATECHOL GROUP

WIPO Patent Application WO/2011/125967

A1

Disclosed is a compound represented by formula (I) (wherein X represents -N=, -CH= or the like; W represents -CH2- or the like; U represents -S- or the like; R1 and R2 each independently represents a hydrogen atom, a halogen atom, an optionally substituted lower alkyl group or the like; R3 represents a hydrogen atom or the like; R4s each independently represents a hydrogen atom, a halogen atom or the like; m represents an integer of 0-2; Q represents a single bond or the like; G represents -C(=O)- or the like; D represents a single bond, -NH- or the like; and E represents a cyclic quaternary ammonium group), an ester of the compound, a protected product of the compound wherein an amino group located on the ring in the side chain in the 7-position is protected, a pharmaceutically acceptable salt of the compound, the ester or the protected product, or a solvate of the compound, the ester, the protected product or the pharmaceutically acceptable salt.

HISAKAWA SHINYA (JP)
HASEGAWA YASUSHI (JP)
AOKI TOSHIAKI (JP)
KUSANO HIROKI (JP)
SANO MASAYUKI (JP)
SATO JUN (JP)
YAMAWAKI KENJI (JP)

PCT/JP2011/058498

October 13, 2011

April 04, 2011

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SHIONOGI & CO (JP)
HISAKAWA SHINYA (JP)
HASEGAWA YASUSHI (JP)
AOKI TOSHIAKI (JP)
KUSANO HIROKI (JP)
SANO MASAYUKI (JP)
SATO JUN (JP)
YAMAWAKI KENJI (JP)

C07D501/46; A61K31/546; A61P31/04; C07D519/06

WO2003078440A1	2003-09-25
WO2010050468A1	2010-05-06
WO2007119511A1	2007-10-25
WO2007096740A2	2007-08-30
WO2003078440A1	2003-09-25
WO2004002472A1	2004-01-08
WO2009055077A1	2009-04-30

JPH03173893A	1991-07-29
JPH02117678A	1990-05-02
JPH0215090A	1990-01-18
JPS62158291A	1987-07-14
JPH03173893A	1991-07-29
JPH0215090A	1990-01-18
JPH0228187A	1990-01-30
JPH02117678A	1990-05-02
JPH06510523A	1994-11-24
JPH05213971A	1993-08-24
JPH0228185A	1990-01-30
JPH06345776A	1994-12-20
JP2009068400W	2009-10-27
JP2010087130A	2010-04-15
JP2010104035A	2010-05-06
JPS60231684A	1985-11-18
JPS62149682A	1987-07-03
JP2010087131A	2010-04-15
US5532235A	1996-07-02
US20080153843A1	2008-06-26

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See also references of EP 2557082A4

TAKAYAMA, Hirotsugu et al. (JP)
Hiromitsu Takayama (JP)

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