Title:
CERAMIC PARTICLE GROUP AND METHOD FOR PRODUCTION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2006/030782
Kind Code:
A1
Abstract:
Provided are a ceramic particle group dispersed in a solvent in a state of primary particles of single crystal, a method for production thereof and a use thereof. One embodiment is a method for producing a sintered particle (ceramic particle) group of hydroxyapatite (HAp), which comprises a step of subjecting a system wherein calcium carbonate is present between primary particles of hydroxyapatite (HAp) to sintering and then dissolving calcium carbonate with water to remove calcium carbonate. A hydroxyapatite (HAp) sintered particle group produced by the above method is a nanometer size particle group having a particle diameter of about 70 to about 120 nm, and is a particle group having a uniform particle diameter (coefficient of variation: 12 %), and further 96 % of the particle group is dispersed as a single crystal particle.
Inventors:
FURUZONO TSUTOMU
OKADA MASAHIRO
OKADA MASAHIRO
Application Number:
PCT/JP2005/016837
Publication Date:
March 23, 2006
Filing Date:
September 13, 2005
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
JAPAN HEALTH SCIENCE FOUND (JP)
FURUZONO TSUTOMU
OKADA MASAHIRO
JAPAN HEALTH SCIENCE FOUND (JP)
FURUZONO TSUTOMU
OKADA MASAHIRO
International Classes:
C01B25/32; A61C13/08; A61F2/28; A61F2/30; A61K6/838; A61L27/00; A61M37/00; B01J20/281; G01N30/88
Foreign References:
| JP2004224674A | 2004-08-12 | |||
| JPH02296711A | 1990-12-07 | |||
| JP2002137910A | 2002-05-14 | |||
| JPS62265108A | 1987-11-18 | |||
| JP2004155596A | 2004-06-03 | |||
| JPH01230413A | 1989-09-13 | |||
| DE10160178A1 | 2002-06-13 | |||
| JP2002137910A | 2002-05-14 | |||
| JP2003055061A | 2003-02-26 |
Other References:
See also references of EP 1808411A4
NOBUYUKI MATSUDA; JO WAKANA; FUMIHIRO KAJI: "Controlling Morphology of Crystals and Crystal Groups of Hydroxyapatite and Related Phosphates", INORGANIC MATERIALS, vol. 2, no. 258, 1995, pages 393 - 400
P.LUO; T.G.NIEH, BIOMATERIALS, vol. 17, 1996, pages 1959
L. J. CUMMINGS; P. TUNON; T. OGAWA, SPEC. PUBL. R. SOC. CHEM., vol. 158, 1994, pages 134
M.FABBRI; G.C. CELOTTI; A. RAVAGLIOLI: "Granulates based on calcium phosphate with controlled morphology and porosity for medical applications: physico-chemical parameters and production technique", BIOMATERIALS, vol. 15, no. 6, 1994
NOBUYUKI MATSUDA; JO WAKANA; FUMIHIRO KAJI: "Controlling Morphology of Crystals and Crystal Groups of Hydroxyapatite and Related Phosphates", INORGANIC MATERIALS, vol. 2, no. 258, 1995, pages 393 - 400
P.LUO; T.G.NIEH, BIOMATERIALS, vol. 17, 1996, pages 1959
L. J. CUMMINGS; P. TUNON; T. OGAWA, SPEC. PUBL. R. SOC. CHEM., vol. 158, 1994, pages 134
M.FABBRI; G.C. CELOTTI; A. RAVAGLIOLI: "Granulates based on calcium phosphate with controlled morphology and porosity for medical applications: physico-chemical parameters and production technique", BIOMATERIALS, vol. 15, no. 6, 1994
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (2-6 Tenjinbashi 2-chome Kita, Kita-k, Osaka-shi Osaka 41, JP)
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