Title:
CEREBLON-BASED HETERODIMERIZABLE CHIMERIC ANTIGEN RECEPTORS
Document Type and Number:
WIPO Patent Application WO/2018/075820
Kind Code:
A3
Abstract:
Provided herein are modified T lymphocytes comprising chimeric receptors and methods thereof.
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Inventors:
XU SHUICHAN (US)
Application Number:
PCT/US2017/057474
Publication Date:
May 31, 2019
Filing Date:
October 19, 2017
Export Citation:
Assignee:
CELGENE CORP (US)
International Classes:
C07K14/705; C07K16/28
Domestic Patent References:
| WO2015127351A1 | 2015-08-27 |
Foreign References:
| US20160264665A1 | 2016-09-15 | |||
| US20160151465A1 | 2016-06-02 |
Other References:
CAMICIA ET AL.: "Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B- cell lymphoma: a comprehensive review", MOLECULAR CANCER, vol. 14, no. 7, 11 December 2015 (2015-12-11), pages 207, XP055309159
WU ET AL.: "Remote control of therapeutic T cells through a small molecule-gated chimeric receptor", SCIENCE, vol. 350, no. 6258, 16 October 2015 (2015-10-16), pages aab4077, XP055260068
KOCOGLU ET AL.: "The Role of Immunotherapy in Multiple Myeloma", PHAMACEUTICALS, vol. 9, no. 1, 14 January 2016 (2016-01-14), pages 3, XP055618884
WU ET AL.: "Remote control of therapeutic T cells through a small molecule-gated chimeric receptor", SCIENCE, vol. 350, no. 6258, 16 October 2015 (2015-10-16), pages aab4077, XP055260068
KOCOGLU ET AL.: "The Role of Immunotherapy in Multiple Myeloma", PHAMACEUTICALS, vol. 9, no. 1, 14 January 2016 (2016-01-14), pages 3, XP055618884
Attorney, Agent or Firm:
GEORGE, Nikolaos, C. et al. (US)
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