Title:
CHEMICAL PROCESS
Document Type and Number:
WIPO Patent Application WO2006064213
Kind Code:
A3
Abstract:
Enzymatic and chemical processes for the preparation of certain of 3-phenyl-2-arylalkylthiopropionic acid derivatives which have utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance and other manifestations of the metabolic syndrome are described and also certain novel intermediates used in these processes.
Inventors:
BROWN DAVID (GB)
GILDAY JOHN PETER (GB)
HOPES PHILIP ANTHONY (GB)
MOSELEY JONATHAN DAVID (GB)
SNAPE EVAN WILLIAM (GB)
WELLS ANDREW (GB)
GILDAY JOHN PETER (GB)
HOPES PHILIP ANTHONY (GB)
MOSELEY JONATHAN DAVID (GB)
SNAPE EVAN WILLIAM (GB)
WELLS ANDREW (GB)
Application Number:
PCT/GB2005/004800
Publication Date:
August 24, 2006
Filing Date:
December 14, 2005
Export Citation:
Assignee:
ASTRAZENECA AB (SE)
ASTRAZENECA UK LTD (GB)
BROWN DAVID (GB)
GILDAY JOHN PETER (GB)
HOPES PHILIP ANTHONY (GB)
MOSELEY JONATHAN DAVID (GB)
SNAPE EVAN WILLIAM (GB)
WELLS ANDREW (GB)
ASTRAZENECA UK LTD (GB)
BROWN DAVID (GB)
GILDAY JOHN PETER (GB)
HOPES PHILIP ANTHONY (GB)
MOSELEY JONATHAN DAVID (GB)
SNAPE EVAN WILLIAM (GB)
WELLS ANDREW (GB)
International Classes:
C12P7/52; C12P11/00; C12P41/00
Domestic Patent References:
WO2003051826A1 | 2003-06-26 | |||
WO2001011073A1 | 2001-02-15 |
Other References:
ZHU J ET AL: "Synthesis of optically pure (S)-2-acetylthio-3-benzenepropanoic acid via enzymatic resolution", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 43, no. 42, 14 October 2002 (2002-10-14), pages 7585 - 7587, XP004383425, ISSN: 0040-4039
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