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Patent Searching and Data


Title:
CHEMOKINE RECEPTOR ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO2001009119
Kind Code:
A3
Abstract:
Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by (I) or (II) and physiologically acceptable salts thereof.

Inventors:
LULY JAY R (US)
NAKASATO YOSHISUKE (JP)
OHSHIMA ETSUO (JP)
SONE HIROKI (JP)
KOTERA OSAMU (JP)
HARRIMAN GERALDINE C B (US)
CARSON KENNETH G (US)
BROWN JAMES A (US)
Application Number:
US0020656W
Publication Date:
August 16, 2001
Filing Date:
July 28, 2000
Export Citation:
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Assignee:
MILLENNIUM PHARM INC (US)
KYOWA HAKKO KOGYO KK (JP)
LULY JAY R (US)
NAKASATO YOSHISUKE (JP)
OHSHIMA ETSUO (JP)
SONE HIROKI (JP)
KOTERA OSAMU (JP)
HARRIMAN GERALDINE C B (US)
CARSON KENNETH G (US)
BROWN JAMES A (US)
International Classes:
A61P29/00; A61P37/08; C07D213/36; C07D213/38; C07D401/06; C07D401/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D451/06; C07D471/10; C07D491/10; C07D495/10; C07D498/10; (IPC1-7): C07D401/06; C07D401/14; C07D405/14; C07D409/14; C07D213/36; C07D491/10; C07D471/10; C07D498/10; C07D495/10; C07D413/14; C07D417/14; C07D451/06; A61K31/4545; A61K31/44; A61P19/02
Domestic Patent References:
WO2000014086A12000-03-16
WO1997044329A11997-11-27
Foreign References:
JPH0543548A1993-02-23
EP0029420A11981-05-27
US4206213A1980-06-03
US3940386A1976-02-24
US3238216A1966-03-01
Other References:
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; BENGTSSON, BENGT OLOF ET AL: "Effects of zimeldine and its metabolites, clomipramine, imipramine and maprotiline in experimental allergic neuritis in Lewis rats", XP002158105, retrieved from STN Database accession no. 117:143039
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; HOEGBERG, THOMAS ET AL: "Stereoconservative reductive methyl- and dimethylamination of isomeric 3,3-diarylpropenals. Synthetic and mechanistic studies on control of the stereochemistry", XP002158106, retrieved from STN Database accession no. 101:190727
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SATO, MAKOTO ET AL: "Psychotropic agents. I. Synthesis of 1-pyridinyl-1-butanones, 1-indolyl-1-butanones and related compounds", XP002158107, retrieved from STN Database accession no. 90:168409
DATABASE WPI Section Ch Week 198128, Derwent World Patents Index; Class B03, AN 1981-50785D, XP002158108
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