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Title:
CHIMERIC ANTIGEN RECEPTOR CONTAINING INTRACELLULAR DOMAIN OF TOLL-LIKE RECEPTOR
Document Type and Number:
WIPO Patent Application WO/2017/024440
Kind Code:
A1
Abstract:
Provided are a chimeric antigen receptor, coding nucleic acid and expression cell thereof, and use thereof in preparation of a tumor-treating drug. An intracellular domain of the chimeric antigen receptor at least comprises an intracellular domain of a toll-like receptor 1 and/or an intracellular domain of a toll-like receptor 2.

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Inventors:
LI PENG (CN)
LAI YUNXIN (CN)
LIN SIMIAO (CN)
YAO YAO (CN)
Application Number:
PCT/CN2015/086352
Publication Date:
February 16, 2017
Filing Date:
August 07, 2015
Export Citation:
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Assignee:
SHENZHEN IN VIVO BIOMEDICINE TECH LTD COMPANY (CN)
International Classes:
C07K19/00; A61P35/00; C07K14/705; C07K16/30; C12N15/62; C12N15/63
Domestic Patent References:
WO2014172584A12014-10-23
Foreign References:
CN104087607A2014-10-08
Other References:
See also references of EP 3202792A4
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
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