CHIMERIC ANTIGEN RECEPTOR FACTORIES AND METHODS OF USE THEREOF

Title:

CHIMERIC ANTIGEN RECEPTOR FACTORIES AND METHODS OF USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2020/113224

Kind Code:

A3

Abstract:

This invention is directed to chimeric antigen receptors and cells comprising the same, wherein the cells further secrete monoclonal antibodies locally at a tumor site.

More Like This:

JP2007509063	Methods for Increasing the CD8 + Cytotoxic T Cell Response and for Treating Multiple Sclerosis
JP2022062020	TUMOR SUPPRESSION USING HUMAN PLACENTAL PERFUSATE AND HUMAN PLACENTA-DERIVED INTERMEDIATE NATURAL KILLER CELLS
JP4526763	Inactivation of MEP pathway genes

Inventors:

MARASCO WAYNE A (US)
ZHU QUAN KAREN (US)
WANG YUFEI (US)
CHANG MATTHEW (US)

Application Number:

PCT/US2019/064032

Publication Date:

August 20, 2020

Filing Date:

December 02, 2019

Export Citation:

Click for automatic bibliography generation Help

Assignee:

DANA-FARBER CANCER INSTITUTE INC (US)

International Classes:

C12N5/0783; A61P35/00; C07K16/28; C07K19/00; C12N5/09

Foreign References:

US20180030147A1	2018-02-01
US20180111992A1	2018-04-26
US9765149B2	2017-09-19

Other References:

SUAREZ ET AL.: "Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model", ONCOTARGET, vol. 7, no. 23, 7 June 2016 (2016-06-07), pages 34341 - 34355, XP055417080

Attorney, Agent or Firm:

ESTRADA DE MARTIN, Paula (US)

Download PDF:

View/Download PDF PDF Help

Previous Patent: DIGITAL IDENTITY MANAGEMENT DEVICE

Next Patent: SYSTEMS AND METHODS FOR IDENTIFYING AN EVENT IN DATA