CHIMERIC ANTIGEN RECEPTOR, AND T CELLS IN WHICH CHIMERIC ANTIGEN RECEPTOR IS EXPRESSED

WIPO Patent Application WO/2017/023138

A1

Disclosed is a chimeric antigen receptor comprising: an antigen-binding domain; a hinge region; a transmembrane domain; a costimulatory domain; and cytoplasmic signaling domain.

KONG SEOGKYOUNG (KR)

PCT/KR2016/008632

February 09, 2017

August 05, 2016

Click for automatic bibliography generation  

YOO YOUNG PHARM CO LTD (KR)

C12N15/62; A61K35/17; C07K16/24; C07K19/00; C12N15/85

US20140271582A1	2014-09-18
US20150139943A1	2015-05-21

KOWOLIK, CLAUDIA M. ET AL.: "CD 28 Costimulation Provided Through a CD 19-specific Chimeric Antigen Receptor Enhances in Vivo Persistence and Antitumor Efficacy of Adoptively Transferred T Cells", CANCER RESEARCH, vol. 66, no. 22, 15 November 2006 (2006-11-15), pages 10995 - 11004, XP055044266
BROWN, CHRISTINE E. ET AL.: "Bioactivity and Safety of IL 13Ralpha2-redirected Chimeric Antigen Receptor CD 8+ T Cells in Patients with Recurrent Glioblastotroma", CLINICAL CANCER RESEARCH, vol. 21, no. 18, 9 June 2015 (2015-06-09), pages 4062 - 4072, XP055362794
JOHNSON, LAURA A. ET AL.: "Rational Development and Characterization of Humanized Anti-EGFR Variant III Chimeric Antigen Receptor T Cells for Glioblastoma", SCIENCE TRANSLATIONAL MEDICINE, vol. 7, no. 275, 18 February 2015 (2015-02-18), pages 1 - 14, XP055362795
See also references of EP 3333264A4

PARK, Jong Hyeok (KR)

View/Download PDF      PDF Help

Previous Patent: METHOD AND APPARATUS FOR GENERATING TRAINING SIGNAL USING PREDETERMINED BINARY SEQUENCE IN WIRELESS ...

Next Patent: AUTOMATIC ALTERNATIVE CONTENT SEARCH APPARATUS FOR VISUALLY IMPAIRED PERSON