CHIMERIC MESENCHYMAL STEM CELL POPULATION AND PREPARATION METHOD THEREFOR, AND METHOD FOR PRODUCING PARATHYROID HORMONE USING TONSIL-DERIVED STEM CELLS

Title:

CHIMERIC MESENCHYMAL STEM CELL POPULATION AND PREPARATION METHOD THEREFOR, AND METHOD FOR PRODUCING PARATHYROID HORMONE USING TONSIL-DERIVED STEM CELLS

Document Type and Number:

WIPO Patent Application WO/2013/162330

Kind Code:

A1

Abstract:

The present invention relates to a method for preparing a chimeric mesenchymal stem cell population comprising a step of mixing and culturing tonsil tissue-derived mesenchymal stem cells obtained from different donors, and a chimeric mesenchymal stem cell population prepared by the method. Additionally, the present invention relates to a method for inducing differentiation of parathyroid tissue cells from tonsil-derived stem cells, a method for producing parathyroid hormones from the parathyroid tissue cells obtained from the method, a cell therapeutic agent including the parathyroid tissue cells for treating hypoparathyroidism or osteoporosis, and a method for treating hypoparathyroidism or osteoporosis using the cell therapeutic agent.

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Inventors:

KIM HAN SU (KR)
WOO SO YOUN (KR)
RYU KYUNG HA (KR)
CHO KYUNG A (KR)
JO IN HO (KR)
PARK YOON SHIN (KR)

Application Number:

PCT/KR2013/003644

Publication Date:

October 31, 2013

Filing Date:

April 26, 2013

Export Citation:

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Assignee:

UNIV EWHA IND COLLABORATION (KR)

International Classes:

C12N5/0775; A61K35/12; C12N1/04; C12N5/02

Foreign References:

KR20090069013A	2009-06-29
US20120088272A1	2012-04-12
US20060182724A1	2006-08-17

Other References:

JANJANIN, SASA ET AL.: "Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells", ARTHRITIS RESEARCH & THERAPY, vol. 10, no. 4, 28 July 2008 (2008-07-28), pages 1 - 12
RYU, KYUNG-HA ET AL.: "Tonsil-derived mesenchymal stromal cells: evaluation of biologic, immunologic and genetic factors for successful banking", CYTOTHERAPY, vol. 14, no. 10, 17 August 2012 (2012-08-17), pages 1193 - 1202

Attorney, Agent or Firm:

SON, MIN (KR)
손민 (KR)

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