Title:
CHIP FOR DETECTING GENETIC MUTATION OF CYTOCHROME P450 GENE AND THE USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2008/011787
Kind Code:
A1
Abstract:
A chip for detecting genetic mutation of cytochrome P450 gene is provided. The chip comprises a solid carrier and probes. The probes can hybridize to the nucleotide sequence and/or its complementary sequence of the cytochrome P450 gene to be detected. Also provided is a method of detecting genetic mutation of cytochrome P450 gene by the chip. The chip can be used to effectively detect the genetic mutation of CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and CYP3A7, and predict the therapeutic efficiency of above 40% of clinical medicaments to realize individuation of medical treatment.
Inventors:
SHENG, Haihui (No.151 Libing Road, Zhang Jiang High-Tech ZonePudong, Shanghai 3, 201203, CN)
盛海辉 (中国上海市浦东张江高科技园区李冰路151号, Shanghai 3, 201203, CN)
盛海辉 (中国上海市浦东张江高科技园区李冰路151号, Shanghai 3, 201203, CN)
Application Number:
CN2007/001853
Publication Date:
January 31, 2008
Filing Date:
June 12, 2007
Export Citation:
Assignee:
SHANGHAI BIOCHIP CO., LTD. (151 Libing Road, Zhang Jiang Hi-Tech ZonePudong, Shanghai 3, 201203, CN)
上海生物芯片有限公司 (中国上海市浦东张江高科技园区李冰路151号, Shanghai 3, 201203, CN)
SHENG, Haihui (No.151 Libing Road, Zhang Jiang High-Tech ZonePudong, Shanghai 3, 201203, CN)
上海生物芯片有限公司 (中国上海市浦东张江高科技园区李冰路151号, Shanghai 3, 201203, CN)
SHENG, Haihui (No.151 Libing Road, Zhang Jiang High-Tech ZonePudong, Shanghai 3, 201203, CN)
International Classes:
C12Q1/68; C12Q1/68
Attorney, Agent or Firm:
DING & ASSOCIATES PATENT TRADEMARK & LAW (2/F 201 Keyuan Road, Zhang Jiang High-Tech Zone, Shanghai 3, 201203, CN)
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